Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 6133
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Final Report Summary - CYTOVOLION (Ion homeostasis and volume regulation of cells and organelles)
When cells are exposed to external solutions that contain less salt, they will swell – a dangerous situation as the cells may even burst and die at some point. Therefore, they must have mechanisms to reduce their volume, a process called regulatory volume decrease. Cell...
Programme: FP7-IDEAS-ERC
Record Number: 202741
Last updated on: 2017-08-14
Periodic Report Summary 2 - ADREEM (Adding Another Dimension – Arrays of 3D Bio-Responsive Materials)
The ADREEM team has been developing new chemistries and new materials that have biological and biomedical applications. For example imagine: • A polymer (we call them “smartpolymers”) that has a drug attached to it, but which only allows the drug to be released when...
Programme: FP7-IDEAS-ERC
Record Number: 202282
Last updated on: 2017-08-14
Mid-Term Report Summary - ROOTS (Role of telomeres and stem cells in ageing)
In our ERC proposal ROOTS we proposed to develop a better understanding of two fundamental aspects of stem cell biology: the molecular mechanisms that regulate cell fate and the role of telomere attrition and numerical chromosomal abnormalities in stem cell depletion. For both...
Programme: FP7-IDEAS-ERC
Record Number: 179460
Last updated on: 2016-04-26
Mid-Term Report Summary - MUDLOC (Multi-Dimensional Lab-On-Chip)
MuDLOC is a multi-dimensional microfluidic based platform for proteomics. The core technology of MuDLOC is a DNA to protein array. This means that a DNA array is turned into a protein by in vitro transcription and translation inside the device, at nanoliter volumes. The...
Programme: FP7-IDEAS-ERC
Record Number: 181994
Last updated on: 2016-05-05
Final Report Summary - ANGIOFAT (New mechanisms of angiogenesis modulators in switching between white and brown adipose tissues)
During this 5-year ERC supported period, we have made significant achievements in understanding the role of vasculatures in modulating adipose tissue functions. We have carefully dissected each of the vascular cellular compartments and signaling pathways that mediate the...
Programme: FP7-IDEAS-ERC
Record Number: 178766
Last updated on: 2016-03-17
Final Report Summary - ALK7 (Metabolic control by the TGF-² superfamily receptor ALK7: A novel regulator of insulin secretion, fat accumulation and energy balance)
This project has unraveled the mechanism by which growth factors of the TGF-beta superfamily and their receptors contribute to fundamental aspects of metabolic regulation, including glucose homeostasis, fat deposition and energy expenditure. Signaling by the ALK7 receptor...
Programme: FP7-IDEAS-ERC
Record Number: 181892
Last updated on: 2016-03-24
Final Report Summary - NANOSYM (Symbiotic bacteria as a delivery system for Nanobodies that target the insect-parasite interplay)
African trypanosomes are unicellular parasites that cause devastating diseases (African Trypanosomiasis) in humans and livestock on the African continent. These parasites are exclusively transmitted by an obligatory blood feeding insect, the tsetse fly, in which the parasite...
Programme: FP7-IDEAS-ERC
Record Number: 195887
Last updated on: 2017-03-10
Final Report Summary - BIOMOLECULAR_COMP (Biomolecular computers)
Biological computers:The intersection of computer science and molecular biology is a fertile ground for new and exciting science. Two notable examples of this are molecular computing and molecular programming. Molecular computing is the use of molecules, and typically...
Programme: FP7-IDEAS-ERC
Record Number: 180511
Last updated on: 2016-03-09
Mid-Term Report Summary - EVOBREED (Evolutionary strategy for plant breeding)
The EVOBREED project considers retrotransposons as an endogenous source of genetic variation and aims to liberate in a controlled fashion their movement and thus induce novel phenotypic diversity to be selected by breeders for improvement of crops. At this stage of the project...
Programme: FP7-IDEAS-ERC
Record Number: 189590
Last updated on: 2016-10-12
Final Report Summary - PLANT CIRES BIOTECH (Functional characterization of plant cellular IRES  in response to abiotic stress and their use as  biotechnological tools)
Plants, as sessile organisms, are constantly exposed to a wide spectrum of stress conditions and are forced to adapt to them in order to complete their life cycle. These environmental stresses, such as heat, drought, high salinity or pathogen attack, severely reduce crop yield...
Programme: FP7-IDEAS-ERC
Record Number: 213793
Last updated on: 2018-01-15
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List retrieved on: 2018-01-18
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