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IN VITRO ANTIOXIDANT ACTIVITY OF SELECTED FOODS |
| Host Laboratory | Scientific Supervisor | |
| United Medical and Dental Schools of Guy's and St Thomas's Hospitals Division of Biochemistry and Molecular Biology Free Radical Research Group London Bridge SE1 9RT London United Kingdom |
Pr. Catherine Rice-Evans Tel : +44 171 955 4240 / Fax : +44 171 955 4983 | |
| Grant Holder | ||
| Dr. Nicoletta Pellegrini (Italian) Tel : 39 2 70600173 / Fax : 39 2 706 38 625 Email : nutr-lab@imiucca.csi.unimi.it | ||
| Abstract Research objectives and content Recent epidemiological observations have demonstrated that polyphenols, especially flavonoids that occur ubiquitously in plants, could contribute to justify the protective effect of vegetable-rich diets. The flavonoids, because of favourable reduction potentials of the phenoxyl radicals, may act as efficient antioxidant. Even though the antioxidant activity of pure substances in relation to their structure has been investigated, information on the total antioxidant activity of more complex matrices as beverages, fruit and vegetables are still lacking. The aim of the project is to establish procedures and adapt current methods in order to evaluate the total antioxidant capacity of vegetable foods as they occur in the human diet. In particular, the research project will involve: a) the study of procedures of simulated digestion for the preparation of food extracts suitable for analysis of antioxidant potential b) the assessment of antioxidant activity (both in aqueous- and in lipophilic- phase) of extracts obtained from different foods. Training content (objective, benefit and expected impact) The training will be aimed to the acquisition of techniques to evaluate the antioxidant potential present in the diet. It will constitute the basis for expanding the ability of the trainee to perform researches on the protection mechanisms against oxidative damage on blood components and to plan further in vivo studies. Links with industry / industrial relevance (22) Contract number : FAIRCT965077 | ||
Last updated :22:01:98
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