Objective Schizophrenia and bipolar affective disorder are a major burden to affected individuals and their families and to society at large. These two severe mental illnesses affect at least 2% of the population worldwide, and whilst 50% of sufferers do not receive adequate treatment, they cost hundreds of billions in healthcare provision, treatments and lost earnings. The current diagnosis of schizophrenia (and bipolar disorder etc.) is rather subjective, not only because of the complex spectrum of symptoms and their similarity to other mental disorders, but also due to the lack of empirical disease markers. This result in long delays (up to 1-3 years) before appropriate therapeutics is prescribed to first episode schizophrenics. Early treatment is associated with greatly improved patient outcomes. There is therefore a major unmet clinical need for empirical diagnostic tests for high throughput screening of biological fluids that would enable early and accurate diagnosis of schizophrenia and related disorders. The identification of specific biomarkers for mental disorders would revolutionise the clinical management of affected individuals. Biomarkers will help in the identification of disease sub-types, aid in predicting and monitoring treatment response and compliance, and identify novel drug targets. If such biomarkers can be found in readily accessible body fluids they open up the possibility of developing new early or pre-symptomatic diagnostics and/or treatments to improve outcomes or even prevent disease. The objective of our project is to identify biomarkers of disease and develop a diagnostic assay panel/tool for the high throughput screening of biological samples for clinical research. Moreover this platform will be utilised by SMEs for drug design and development for mental disorders research into new animal models for mental dirders and identifying biomarkers for other mental disorders Fields of science medical and health sciencesbasic medicinemedicinal chemistrymedical and health sciencesclinical medicinepsychiatryschizophrenia Keywords Clinical research bipolar disorder early diagnosis high throughput technologies mental disorders proteomics schizophrenia Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2007-1.1-4 - SME-driven collaborative research projects for developing tools and technologies for high-throughput research Call for proposal FP7-HEALTH-2007-B See other projects for this call Funding Scheme CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinator Psynova Neurotech Ltd EU contribution € 373 354,00 Address St, Johns Innovation Centre, Cowley Road CB4 0WS Cambridge United Kingdom See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Barbara Baron (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution € 463 290,00 Address TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Administrative Contact Dawn Barker (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT Germany EU contribution € 360 387,00 Address Square J 5 68159 Mannheim See on map Region Baden-Württemberg Karlsruhe Mannheim, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Simone Fuchs (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Westfälische Wilhelms-Universität Münster Germany EU contribution € 360 387,00 Address SCHLOSSPLATZ 2 48149 MUENSTER See on map Region Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Karl-Heinz Runde (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data EDI Experimentelle Diagnostische Immunologie GmbH Germany EU contribution € 301 300,00 Address Aspenhaustrasse 72770 Reutlingen See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Thomas Joos (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data PERA INNOVATION LIMITED United Kingdom EU contribution € 175 220,00 Address Innovation Park, Nottingham Road LE13 OPB MELTON MOWBRAY, LEICESTERSHIRE See on map Activity type Research Organisations Administrative Contact David Cartlidge (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED Ireland EU contribution € 206 050,00 Address FOSTERS AVENUE MOUNT MERRION 4 Blackrock Dublin See on map Region Ireland Eastern and Midland Dublin Activity type Other Administrative Contact Pauline Rudd (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STORKBIO Estonia EU contribution € 147 056,00 Address LAKI 25 12915 TALLINN See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Kristi Kurg (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MYRIAD RBM INC CORPORATION United States EU contribution € 370 644,00 Address Duval Road 3300 TX 78759 Austin See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Sam Labrie (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data