Objective The project addresses the mechanical bases of cell motility by swimming and crawling, and the possibility of replicating the principles behind them in artificial systems.The goals are to elucidate some key mechanisms governing bio-locomotion. In particular, actin- based motility of crawling cells and motility by swimming of unicellular organisms will be studied both in general and with reference to concrete model systems.The study of biological examples of swimming and crawling motility will be used to produce a prototype of a micron-scale bio-inspired motile micro-robot exploiting the miniaturization that becomes possible from the extensive use of active materials.This is a multi-disciplinary research project. The themes arise from the Mechanics of Soft and Bio- logical Matter. The methods are those of Computational Engineering, and take advantage of innovative techniques from Applied Mathematics. The planned research activities rest on the development of new tools and methods in mathematical modeling, numerical simulation, data acquisition on biological systems, and on the construction of prototype devices.*** Fields of science natural sciencescomputer and information sciencescomputational sciencemultiphysicsnatural sciencesmathematicsapplied mathematicsmathematical model Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-AG-PE8 - ERC Advanced Grant - Products and process engineering Call for proposal ERC-2013-ADG See other projects for this call Funding Scheme ERC-AG - ERC Advanced Grant Host institution SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE EU contribution € 1 302 270,00 Address VIA BONOMEA 265 34136 Trieste Italy See on map Region Nord-Est Friuli-Venezia Giulia Trieste Activity type Higher or Secondary Education Establishments Administrative Contact Gabriele Rizzetto (Mr.) Principal investigator Antonio De Simone (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE Italy EU contribution € 1 302 270,00 Address VIA BONOMEA 265 34136 Trieste See on map Region Nord-Est Friuli-Venezia Giulia Trieste Activity type Higher or Secondary Education Establishments Administrative Contact Gabriele Rizzetto (Mr.) Principal investigator Antonio De Simone (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data