Objective Molecular analysis of exhaled breath is a new frontier in medical testing with an enormous potential for monitoring respiratory disease.Breath tests are non-invasive and require minimal patient effort. This makes them applicable in a wide range of settings varying from theintensive care unit (ICU) to home. Respiratory infections are the primary cause of death in ICU. More than half of the patients in ICUsworldwide suffer from infections, which lengthen their hospital stays and increase their mortality rate. Timely detection and treatment isimportant and monitoring infection via breath analysis will have a major impact on healthcare. Electronic nose sensor technology is beingdeveloped but there is a need for clinical validation. Also it is not always clear to which specific compounds these sensors are sensitive. Inthis proposal the focus is on developing a sensor technique, where measurements are obtained and processed at the bedside. Thissolution will be dedicated to the detection of infection from breath. A synergistic approach is proposed between sensor technologydevelopment, clinical validation and complex data interpretation. Knowledge will be exchanged between an industrial partner (Philips, NL)strongly involved in the healthcare and well-being markets, two academic partners (University of Manchester, UK, Academic MedicalCentre, NL) that have an impressive track record in breath analysis research in a clinical environment and a research institution (University of Twente, NL) that has promising potential on bedside gas sensor technology that can be tailored to compounds of interest. The inter-sectorialknowledge transfers as defined in this proposal are key to the success of this ambitious goal. The project consists of 6 highly multidisciplinarywork packages, which involve sensor development, clinical measurements and validation studies and the development ofcomplex data analysis tools. Fields of science natural sciencescomputer and information sciencesdata sciencesocial sciencessociologydemographymortalitymedical and health sciencesclinical medicinecritical care medicinemedical and health scienceshealth sciencesinfectious diseasesRNA virusescoronavirusesengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2013-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Call for proposal FP7-PEOPLE-2013-IAPP See other projects for this call Funding Scheme MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinator ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM EU contribution € 201 834,33 Address MEIBERGDREEF 15 1105AZ Amsterdam Netherlands See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Administrative Contact Rebecca Massonet (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all PHILIPS ELECTRONICS NEDERLAND BV Netherlands EU contribution € 387 802,93 Address HIGH TECH CAMPUS 52 5656 AG Eindhoven See on map Region Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Veronika Kiss (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE UNIVERSITY OF MANCHESTER United Kingdom EU contribution € 244 978,80 Address OXFORD ROAD M13 9PL Manchester See on map Region North West (England) Greater Manchester Manchester Activity type Higher or Secondary Education Establishments Administrative Contact Claire Faichnie (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITEIT TWENTE Netherlands EU contribution € 43 332,91 Address DRIENERLOLAAN 5 7522 NB Enschede See on map Region Oost-Nederland Overijssel Twente Activity type Higher or Secondary Education Establishments Administrative Contact Ferdinand Damhuis (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data