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Commercialising MR-HIFU: an Image-Guided Local Drug-Delivery Platform

Objetivo

Reducing the high attrition rates in drug development continues to be a key challenge for the pharmaceutical industry. With average drug development costs of over $2 billion dollar and a 95% failure rate of cancer drugs in Phase I trials, a new paradigm is highly needed.
iGOLDD represents a unique opportunity for the commercialisation of a powerful alternative drug-delivery solution that has the potential to locally boost the efficacy of many drugs for a range of clinical indications. Prof. Moonen and his team, as part of the ERC project Sound Pharma, have developed a powerful technology platform, based on magnetic resonance guided focused ultrasound (MR-HIFU), that can be used for high-precision image-guided drug delivery, HIFU is the only known technique capable of completely non-invasive, precisely controlled heating deep inside the human body. MRI allows continuous imaging of the tumour and surrounding health tissue for target definition.
iGOLDD aims to commercialise this unique technology as a stand-alone drug delivery platform that can be widely offered to pharmaceutical and biotechnology companies to improve new or existing drugs or reuse shelved therapies. In iGOLDD we will further optimise the HIFU technology (in particular temperature control and motion correction) for drug delivery of macromolecular drugs, such as antibody-drug conjugates, to demonstrate the large potential of our drug delivery platform. In addition, we will prepare for market introduction, by defining the exact business strategy, model and positioning for commercial success. We will develop the business strategy that offers the most promise, based on the technological aspects of the project, the market needs and trends, the end-user needs and the IP-position. During this project, we will gain technical and commercial proof-of-concept, which will provide us with the necessary information regarding potential commercialisation routes.

Ámbito científico

CORDIS clasifica los proyectos con EuroSciVoc, una taxonomía plurilingüe de ámbitos científicos, mediante un proceso semiautomático basado en técnicas de procesamiento del lenguaje natural.

Régimen de financiación

ERC-POC - Proof of Concept Grant

Institución de acogida

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Aportación neta de la UEn
€ 150 000,00
Dirección
HEIDELBERGLAAN 100
3584 CX Utrecht
Países Bajos

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Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 150 000,00

Beneficiarios (1)