Skip to main content

EUCANCan: a federated network of aligned and interoperable infrastructures for the homogeneous analysis, management and sharing of genomic oncology data for Personalized Medicine.

Objective

We propose to create the EUropean-CANadian Cancer network (EUCANCan), a federated infrastructure whose mission is to enable Personalized Medicine in Oncology by promoting the generation and sharing of harmonized genomic and phenotypic data. EUCANCan builds on work performed by members of the consortium and related projects to align and interconnect existing European and Canadian infrastructures for the analysis and management of genomic oncology data. The EUCANCan network will be composed of reference nodes in Amsterdam, Barcelona, Berlin, Heidelberg, Paris and Toronto which have established strong research and clinical programs in the field of genomic oncology. These reference nodes will work together in an interoperable fashion to provide the genomic oncology community with a uniform computing environment for the processing, harmonization and secure sharing of cancer genome and phenome data in the context of clinical research, enabling the discovery of clinically-relevant patterns of variation in the cancer genome such as biomarkers predictive of therapeutic response. The infrastructure will also provide a proving ground for federated genome analysis systems that may one day be integrated into national and regional healthcare systems.

EUCANCan’s objectives are: (1) harmonise protocols for the identification and interpretation of germline and somatic variation profiles within cancer genomes; (2) generate strategies for the flow, management, storage and distribution of data within and across EUCANCan nodes; (3) define community standards for data elements, types and formats; (4) develop an open and accessible data portals for the searching and download of EUCANCan data; and (5) define an appropriate ethical and legal frame to ensure the secure sharing of protected individual genomic and phenotypic data across countries.

Field of science

  • /medical and health sciences/clinical medicine/oncology/cancer
  • /natural sciences/biological sciences/genetics and heredity/genome
  • /medical and health sciences/clinical medicine/oncology

Call for proposal

H2020-SC1-2018-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION
Address
Calle Jordi Girona 31
08034 Barcelona
Spain
Activity type
Research Organisations
EU contribution
€ 774 750

Participants (17)

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 323 500
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
Ontario Institute for Cancer Research
Canada
EU contribution
€ 0
Address
661 University Avenue, Suite 510
M5G 0 A3 Toronto, Ontario
Activity type
Research Organisations
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 171 250
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
STICHTING HARTWIG MEDICAL FOUNDATION
Netherlands
EU contribution
€ 530 650
Address
Science Park 408
1098 XH Amsterdam
Activity type
Research Organisations
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 468 700
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 383 337,50
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
EU contribution
€ 218 343,75
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
INSTITUT CATALA D'ONCOLOGIA
Spain
EU contribution
€ 196 435
Address
Av Gran Via De L'hospitalet 199-203
08908 L'hospitalet Del Llobregat
Activity type
Research Organisations
FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON
Spain
EU contribution
€ 343 687,50
Address
Calle Nazaret 115-117
08035 Barcelona
Activity type
Research Organisations
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
EU contribution
€ 617 550
Address
Im Neuenheimer Feld 672
69120 Heidelberg
Activity type
Higher or Secondary Education Establishments
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 615 000
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
INSTITUT CURIE
France
EU contribution
€ 534 250
Address
Rue D'ulm 26
75231 Paris
Activity type
Research Organisations
ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY
Canada
EU contribution
€ 0
Address
845 Sherbrooke Street West
H3A0G4 Montreal
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA
Spain
EU contribution
€ 155 875
Address
Barrio Sarriena S N
48940 Leioa
Activity type
Higher or Secondary Education Establishments
HEIDELBERGER AKADEMIE DER WISSENSCHAFTEN
Germany
EU contribution
€ 287 500
Address
Karlstrasse 4
69117 Heidelberg
Activity type
Research Organisations
LINQ MANAGEMENT GMBH
Germany
EU contribution
€ 295 656
Address
Friedbergstraße 35
14057 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STEINBEIS TRANSFER GMBH
Germany
EU contribution
€ 82 968
Address
Willi Bleicher Strasse 19
70174 Stuttgart
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)