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EUCANCan: a federated network of aligned and interoperable infrastructures for the homogeneous analysis, management and sharing of genomic oncology data for Personalized Medicine.

Descripción del proyecto

Una red de medicina personalizada en oncología

La iniciativa EUCANCan, financiada por la Unión Europea, interconectará infraestructuras europeas y canadienses dedicadas al análisis y la gestión de datos genómicos con aplicaciones oncológicas. La plataforma generará un entorno informático uniforme para el procesamiento de datos genómicos y fenotípicos del cáncer. El portal de datos abierto y accesible seguirá las pautas éticas y legales apropiadas para el intercambio seguro de datos. El objetivo a largo plazo es aprovechar la plataforma a fin de orientar la investigación futura hacia la identificación de patrones de variación clínicamente relevantes en el genoma del cáncer, como los biomarcadores predictivos de la respuesta terapéutica.

Objetivo

We propose to create the EUropean-CANadian Cancer network (EUCANCan), a federated infrastructure whose mission is to enable Personalized Medicine in Oncology by promoting the generation and sharing of harmonized genomic and phenotypic data. EUCANCan builds on work performed by members of the consortium and related projects to align and interconnect existing European and Canadian infrastructures for the analysis and management of genomic oncology data. The EUCANCan network will be composed of reference nodes in Amsterdam, Barcelona, Berlin, Heidelberg, Paris and Toronto which have established strong research and clinical programs in the field of genomic oncology. These reference nodes will work together in an interoperable fashion to provide the genomic oncology community with a uniform computing environment for the processing, harmonization and secure sharing of cancer genome and phenome data in the context of clinical research, enabling the discovery of clinically-relevant patterns of variation in the cancer genome such as biomarkers predictive of therapeutic response. The infrastructure will also provide a proving ground for federated genome analysis systems that may one day be integrated into national and regional healthcare systems.

EUCANCan’s objectives are: (1) harmonise protocols for the identification and interpretation of germline and somatic variation profiles within cancer genomes; (2) generate strategies for the flow, management, storage and distribution of data within and across EUCANCan nodes; (3) define community standards for data elements, types and formats; (4) develop an open and accessible data portals for the searching and download of EUCANCan data; and (5) define an appropriate ethical and legal frame to ensure the secure sharing of protected individual genomic and phenotypic data across countries.

Convocatoria de propuestas

H2020-SC1-BHC-2018-2020

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Convocatoria de subcontratación

H2020-SC1-2018-Single-Stage-RTD

Régimen de financiación

RIA - Research and Innovation action

Coordinador

BARCELONA SUPERCOMPUTING CENTER CENTRO NACIONAL DE SUPERCOMPUTACION
Aportación neta de la UEn
€ 774 750,00
Dirección
CALLE JORDI GIRONA 31
08034 Barcelona
España

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Región
Este Cataluña Barcelona
Tipo de actividad
Research Organisations
Enlaces
Coste total
€ 774 750,00

Participantes (19)