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Identification of the Molecular Mechanisms of non-response to Treatments, Relapses and Remission in Autoimmune, Inflammatory, and Allergic Conditions

Project description

Identifying reasons for patients’ negative response to treatment

The identification of the molecular mechanisms that can positively or negatively influence a patient’s response to medical treatment is a key issue among health practitioners. A study promoted by 3TR, a consortium of university institutions, SMEs and leading pharmaceutical companies, will address this issue. This EU-funded project will apply bioinformatics and control methods to collect and analyse data from blood, tissues and other fluids during the entire treatment process. It will create a centralised data platform for better management and implement an inclusive molecular and clinical picture of patients experiencing similar diseases. The project intends to explain the role that our microbiome, genetics and regulatory genomics play during treatment.

Field of science

  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug
  • /natural sciences/biological sciences/genetics and heredity

Call for proposal

H2020-JTI-IMI2-2018-14-two-stage
See other projects for this call

Funding Scheme

IMI2-RIA - Research and Innovation action
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Address
Avenida Americo Vespucio 15 Edif S2
41092 Sevilla
Spain
Activity type
Research Organisations
EU contribution
€ 9 876 529,68

Participants (69)

THE UNIVERSITY OF MANCHESTER
United Kingdom
EU contribution
€ 682 941,25
Address
Oxford Road
M13 9PL Manchester
Activity type
Higher or Secondary Education Establishments
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
Germany
EU contribution
€ 2 700 000
Address
Olshausenstrasse 40
24118 Kiel
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF LEICESTER
United Kingdom
EU contribution
€ 523 897,95
Address
University Road
LE1 7RH Leicester
Activity type
Higher or Secondary Education Establishments
EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH
Germany
EU contribution
€ 1 917 499,43
Address
Heinrich-hertz-allee 1
66386 St Ingbert
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 1 665 250
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
EUROPEAN RESPIRATORY SOCIETY
Switzerland
EU contribution
€ 361 390,08
Address
Avenue Sainte Luce 4
1003 Lausanne
Activity type
Other
FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO
Italy
EU contribution
€ 815 450
Address
Via Francesco Sforza 28
20122 Milano
Activity type
Other
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
EU contribution
€ 717 221,25
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
EU contribution
€ 120 875
Address
Hanzeplein 1
9713 GZ Groningen
Activity type
Higher or Secondary Education Establishments
ALACRIS THERANOSTICS GMBH
Germany
EU contribution
€ 106 250
Address
Max Planck Strasse 3
12489 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ATRYS HEALTH, SA
Spain
EU contribution
€ 237 562,50
Address
Calle Velazquez 24 4 Izquierda
28001 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AZIENDA OSPEDALE UNIVERSITA PADOVA
Italy
EU contribution
€ 277 003,50
Address
Via Nicolo Giustiniani 1
35128 Padova
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
AZIENDA OSPEDALIERO-UNIVERSITARIA ANNA MEYER
Italy
EU contribution
€ 146 350
Address
Viale Pieraccini 24
50139 Firenze
Activity type
Research Organisations
UNIVERSITEIT GENT
Belgium
EU contribution
€ 141 508
Address
Sint Pietersnieuwstraat 25
9000 Gent
Activity type
Higher or Secondary Education Establishments
UNIVERSITAIR ZIEKENHUIS GENT

Participation ended

Belgium
EU contribution
€ 0
Address
Corneel Heymanslaan 10
9000 Gent
Activity type
Research Organisations
REGION HOVEDSTADEN
Denmark
EU contribution
€ 201 780
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE NANCY
France
EU contribution
€ 825 030,63
Address
Avenue Mar De Lattre Tassigny 29
54035 Nancy Cedex
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF GLASGOW
United Kingdom
EU contribution
€ 201 000
Address
University Avenue
G12 8QQ Glasgow
Activity type
Higher or Secondary Education Establishments
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 541 266,25
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 287 500
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
EU contribution
€ 1 573 843,06
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.
Spain
EU contribution
€ 201 512,74
Address
Calle Monforte De Lemos 5
28029 Madrid
Activity type
Research Organisations
Deutsches Rheuma-Forschungszentrum Berlin
Germany
EU contribution
€ 229 595
Address
Chariteplatz 1
10117 Berlin
Activity type
Research Organisations
EUROPEAN FEDERATION OF ASTHMA &ALLERGY ASSOCIATIONS IDEELL FORENING
Belgium
EU contribution
€ 70 416,25
Address
Rue Du Congrès 35
1000 Brussels
Activity type
Other
EUROPEAN LUNG FOUNDATION
United Kingdom
EU contribution
€ 110 675
Address
Glossop Road 442
S10 2PX Sheffield
Activity type
Other
GENOS DOO ZA VJESTACENJE I ANALIZU
Croatia
EU contribution
€ 106 501,56
Address
Vatrogasna 112
31000 Osijek
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 241 798,96
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 125 000
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
Portugal
EU contribution
€ 290 996,25
Address
Avenida Prof Egas Moniz
1649 028 Lisboa
Activity type
Research Organisations
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 584 499,25
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
LUPUS EUROPE
United Kingdom
EU contribution
€ 78 750
Address
St James House, 27-43 Eastern Road
RM1 3NH Romford Essex
Activity type
Other
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 565 627,50
Address
Hofgartenstrasse 8
80539 Muenchen
Activity type
Research Organisations
MEDIZINISCHE HOCHSCHULE HANNOVER
Germany
EU contribution
€ 285 965
Address
Carl-neuberg-strasse 1
30625 Hannover
Activity type
Higher or Secondary Education Establishments
OREBRO UNIVERSITY
Sweden
EU contribution
€ 893 122,25
Address
Fakultetsgatan 1
70182 Orebro
Activity type
Higher or Secondary Education Establishments
OWLSTONE MEDICAL LIMITED
United Kingdom
EU contribution
€ 139 500
Address
183 Cambridge Science Park, Milton Road
CB4 0GA Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PHILIPPS UNIVERSITAET MARBURG
Germany
EU contribution
€ 201 565
Address
Biegenstrasse 10
35037 Marburg
Activity type
Higher or Secondary Education Establishments
QUEEN MARY UNIVERSITY OF LONDON
United Kingdom
EU contribution
€ 2 320 291,36
Address
327 Mile End Road
E1 4NS London
Activity type
Higher or Secondary Education Establishments
SERVICIO ANDALUZ DE SALUD
Spain
EU contribution
€ 1 429 125
Address
Avenida De La Constitucion 18
41071 Sevilla
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SERVICIO MADRILENO DE SALUD
Spain
EU contribution
€ 387 450
Address
Plaza Carlos Trias Bertran 7
28020 Madrid
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SIP SERVICE S.R.L.
Italy
EU contribution
€ 201 500
Address
Via San Gregorio 12
20124 Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SOCIETE DE PNEUMOLOGIE DE LANGUE FRANCAISE
France
EU contribution
€ 196 425
Address
66 Boulevard Saint Michel
75006 Paris 6
Activity type
Other
STICHTING VUMC
Netherlands
EU contribution
€ 836 688,75
Address
De Boelelaan 1117
1081 HV Amsterdam
Activity type
Research Organisations
TECHNISCHE UNIVERSITAET DRESDEN
Germany
EU contribution
€ 192 500
Address
Helmholtzstrasse 10
01069 Dresden
Activity type
Higher or Secondary Education Establishments
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 1 170 877,75
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
THE QUEEN'S UNIVERSITY OF BELFAST
United Kingdom
EU contribution
€ 161 201,50
Address
University Road Lanyon Building
BT7 1NN Belfast
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI CATANIA
Italy
EU contribution
€ 145 302,50
Address
Piazza Universita 2
95131 Catania
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO
Italy
EU contribution
€ 294 944,75
Address
Duomo 6
13100 Vercelli
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI CAGLIARI
Italy
EU contribution
€ 294 924,76
Address
Via Universita 40
09124 Cagliari
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI GENOVA
Italy
EU contribution
€ 236 249,38
Address
Via Balbi 5
16126 Genova
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DI PISA
Italy
EU contribution
€ 292 500
Address
Lungarno Pacinotti 43/44
56126 Pisa
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT BASEL
Switzerland
EU contribution
€ 489 568,75
Address
Petersplatz 1
4051 Basel
Activity type
Higher or Secondary Education Establishments
CLINIQUES UNIVERSITAIRES SAINT-LUC
Belgium
EU contribution
€ 354 942,75
Address
Avenue Hippocrate 10
1200 Bruxelles
Activity type
Research Organisations
UNIVERSITE DE BRETAGNE OCCIDENTALE
France
EU contribution
€ 328 000
Address
Rue Des Archives 3
29238 Brest
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT HASSELT
Belgium
EU contribution
€ 247 825
Address
Martelarenlaan 42
3500 Hasselt
Activity type
Higher or Secondary Education Establishments
UNIVERSITETET I BERGEN
Norway
EU contribution
€ 209 617,50
Address
Museplassen 1
5020 Bergen
Activity type
Higher or Secondary Education Establishments
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 343 955,31
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 560 011,25
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 890 500
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 201 498,10
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
UNIVERSYTET MEDYCZNY W LODZI.
Poland
EU contribution
€ 80 600
Address
Al. Kosciuszki, 4
90419 Lodz
Activity type
Higher or Secondary Education Establishments
VIB VZW
Belgium
EU contribution
€ 361 018,75
Address
Rijvisschestraat 120
9052 Zwijnaarde - Gent
Activity type
Research Organisations
SANOFI-AVENTIS DEUTSCHLAND GMBH
Germany
EU contribution
€ 0
Address
Bruningstrasse 50
65929 Frankfurt Am Main
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
JANSSEN PHARMACEUTICA NV
Belgium
EU contribution
€ 0
Address
Turnhoutseweg 30
2340 Beerse
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TAKEDA DEVELOPMENT CENTRE EUROPE LTD
United Kingdom
EU contribution
€ 0
Address
Aldwych 61
WC2B 4AE London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASTRAZENECA AB
Sweden
EU contribution
€ 0
Address
Vastra Maelarhamnen
151 85 Sodertaelje
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD.
United Kingdom
EU contribution
€ 0
Address
Great West Road 980
TW89GS Brentford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NOVARTIS PHARMA AG
Switzerland
EU contribution
€ 0
Address
Lichtstrasse 35
4056 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PFIZER LIMITED
United Kingdom
EU contribution
€ 0
Address
Ramsgate Road
CT13 9NJ Sandwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
F. HOFFMANN-LA ROCHE AG
Switzerland
EU contribution
€ 0
Address
Grenzacherstrasse 124
4070 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)