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Molecular atlas of the brain across the human lifespan

Project description

Molecular atlas of the brain in the Human Cell Atlas initiative

The goal of the EU-funded BRAINTIME project is to contribute to the Human Cell Atlas initiative by delivering major new data-sets on human brain development and ageing. World-leading international laboratories in the field of single-cell genomics and multi-omics will collaborate on this project. Researchers will analyse the developing human midbrain and hindbrain to generate an atlas of monoaminergic cell populations in both healthy brain and in neurodegenerative cases. They will embed the new cell type maps into 3D contexts and temporal developmental models. BRAINTIME will establish protocols and algorithms to allow flexible model testing and perturbation analysis on midbrain and hindbrain tissues as well as brain tissue analysis at single-cell level, that can be used to probe other brain regions and other human tissues.

Call for proposal

H2020-SC1-2019-Single-Stage-RTD
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Funding Scheme

RIA - Research and Innovation action

Coordinator

KAROLINSKA INSTITUTET
Address
Nobels Vag 5
17177 Stockholm
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 198 068,75

Participants (4)

WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 1 095 000
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
EU contribution
€ 998 468,75
Address
Raemistrasse 101
8092 Zuerich
Activity type
Higher or Secondary Education Establishments
ALLEN INSTITUTE
United States
EU contribution
€ 936 513,75
Address
615 Westlake Ave N
98109 Seattle Wa
Activity type
Research Organisations
CARTANA AB
Sweden
EU contribution
€ 100 000
Address
Nobels Vag 3
171 65 Solna
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)