Objective
- Monitoring schistosome-polluted water by PCR;
- Monitoring of schistosome-infected snails by detecting schistosomal antigens and by PCR;
- Monitoring the ratio of prepatent/patent infections in snails for rapid preliminary assessment of schistosomiasis prevalence in humans;
- Monitoring of snails prepatent/patent infections after mass-treatment for possible timing of retreatment;
- Develop DNA and antigen-based technologies for monitoring Sm and Sh in water and in snails.
Expected Outcome
- Development of a rapid testing system for identification of schistosome infected snails.
- Preparation of monoclonal antibodies (Mab) for detection of S. haematobium infected snails;
- Monitoring snails for infection by detecting schistosomal antigens;
- Developing PCR-based tools for monitoring schistosomes in water and snails;
- Monitoring of schistosome infestation of water by PCR;
- Collection of biological materials in the field for development of the monitoring tools;
- Evaluation the relation between human infection and prepatent/patent infection in snails;
- Examining the fall and rise of prepatent/patent ratio of snail infection after mass treatment;
- Preparation for an organisation of field studies involved in tasks no 2, 4, 5, 6 and 7.
Topic(s)
Data not availableCall for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
69120 Heidelberg
Germany