It is the aim of the current project to combine the research skills, interests and resources of research groups in cognitive and clinical neuropsychology with those of research groups in psychopharmacology and neuroimaging for a concerted effort at illuminating some basic problems in visual object recognition.
The studies are based on a cognitive model of visual object recognition, and designed to provide answers to unclear issues particularly relating to intermediate stages of visual perception. Specifically, it is planned to study the cerebral organization of processes in form perception, focusing on the integration of form elements into whole perceptions. This will be done by conducting clinical neuropsychological studies of patients with infarcts in the territory of the posterior cerebral artery (in two centers to recruit a sufficient number of patients), and to relate selective deficits of form perception to the localization of lesions on Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). In selected patients the nature of deficits will be studied with cognitive experimental measures in a multiple case study approach. The same processes of form perception will be studied in normal subjects in psychopharmacological studies and in a series of experiments using neuroimaging techniques (Positron Emission Tomography (PET) and functional MRI (fMRI)).
In neuroimaging, the plans include comparisons of PET and fMRI in the cognitive activation studies. The cognitive data will also be used in further developments of the imaging data analyses with the specific goals of increasing spatial resolution and modeling non-linear relationships, and making these generally available in a MATLAB toolbox.
Funding SchemeCSC - Cost-sharing contracts