Objective The overall objectives of the HepCVax cluster is to identify viral and host mechanisms which are involved in(I) viral replication and particle formation,(ii) pathogen city and viral persistence and, based on the knowledge of virus properties as well as virus-host interactions and pathogenesis,(iii) to identify innovative antiviral and immunotherapeutic strategies capable of inducing a broad and sustained HCV specific cellular-mediated immune responses. All information emerging from the understanding of the HCV genome will be integrated in the first ever-European sequence database dedicated to Hepatitis C virus. The cluster will be subdivided in three component Networks. Whereas HepCVax-PARTIC will concentrate on the molecular and intracellular level of the virus-host interactions through the identification of factors involved in HCV-particles formation, HepCVax.IMPA TH will focus on the interaction between HCV and different arms of the innate and adaptive immune response. HepCVax-PRECLIN will exploit the expected discoveries made by Networks 1 and 2 to develop and test new immunotherapeutic strategies in vitro and in small animal models. Fields of science natural sciencescomputer and information sciencesdatabasesnatural sciencesbiological sciencesmicrobiologyvirologymedical and health scienceshealth sciencesinfectious diseasesRNA viruseshepatitis Cmedical and health sciencesbasic medicineimmunologynatural sciencesbiological sciencesgeneticsgenomes Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator LEIDEN UNIVERSITY EU contribution No data Address Albinusdreef 2 2300 RC LEIDEN Netherlands See on map Total cost No data Participants (15) Sort alphabetically Sort by EU Contribution Expand all Collapse all ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Germany EU contribution No data Address Hugstetterstr. 55 79106 FREIBURG (IN BREISGAU) See on map Total cost No data BIOMERIEUX SA France EU contribution No data Address CERVI - 21, Av. Tony Garnier 69365 LYON See on map Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution No data Address Rue du Professeur Calmette 1 59021 LILLE See on map Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution No data Address AllTe d'Italie 46 69364 LYON See on map Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution No data Address 7,Passage du Vercors 7 69367 LYON See on map Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution No data Address Rue Koeberle 3 ADR 16 - Alsace 67000 Strasbourg See on map Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution No data Address 46, Allee d'Italie 69634 VENISSIEUX See on map Total cost No data LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH Germany EU contribution No data Address Marchioninistr. 15 81377 MUENCHEN See on map Total cost No data PEVION BIOTECH AG Switzerland EU contribution No data Address Rehhagstrasse 79 3018 BERN See on map Total cost No data THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD United Kingdom EU contribution No data Address John Radcliffe Hospital - Oxfordshire 5802 OX3 9DU OXFORD/HEADINGTON See on map Total cost No data UNIVERSITA DEGLI STUDI DI BARI Italy EU contribution No data Address Piazza Umberto I Palazzo Ateneo 1 70121 BARI See on map Total cost No data UNIVERSITAETSKLINIKUM HEIDELBERG Germany EU contribution No data Address Otto-Meyerhof-Zentrum, Im Neuenheimer Feld 324 69120 HEIDELBERG See on map Total cost No data UNIVERSITE CLAUDE BERNARD LYON 1 France EU contribution No data Address Passage du Vercors 7 69367 LYON See on map Total cost No data UNIVERSITE DE PARIS V 'RENÉ DESCARTES' France EU contribution No data Address 156,Rue de Vaugirard 156, CHU Necker 75730 PARIS See on map Total cost No data UNIVERSITY OF BERNE Switzerland EU contribution No data Address 49,Murtenstrasse 35 3010 BERN See on map Total cost No data