In the 21st century, Europe will face the burden of its ageing population. The most common sensory impairment among the elderly is age related hearing impairment (ARHI). In this project, we want to identify the ethiological factors involved in ARHI, including the genetic causes, the environmental causes and the interaction between them. A large cohort of patients and controls, originating from various parts of Europe, will be subjected to audiologic evaluation, genetic analysis and a questionnaire on suspected environmental risks. We expect to identify the major susceptibility genes and clarify the role of environmental risk factors. The interaction between the different factors will be studied using neural network computing. Based upon these results, guidelines will be formulated for the prevention of ARHI.
Funding SchemeCSC - Cost-sharing contracts
2400 NV Koepenhagen
CF14 4XN Cardiff
92121-1975 San Diego
6500 HB Nijmegen