CORDIS
EU research results

CORDIS

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Cognitive and Cerebrovascular Effects Induced by Low Dose Ionising Radiation

Project information

Grant agreement ID: 295552

Status

Closed project

  • Start date

    1 October 2011

  • End date

    31 March 2015

Funded under:

FP7-EURATOM-FISSION

  • Overall budget:

    € 4 905 635,40

  • EU contribution

    € 2 999 516,80

Coordinated by:

STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE

Belgium

Objective

The major elements of scientific uncertainty in the context of radiation protection policy and of risk assessment for cerebrovascular diseases, set the following key topics (1) the direct assessment of health effects through epidemiological studies of groups exposed to low doses, (2) doses-response and biological effects from different types of radiation and (3) the biological processes in cells and tissues mediating the cerebrovascular effects of low-dose radiation. These 3 topics have been identified as priorities by the HLEG, the MELODI Strategic Agenda and ARCH (Agenda for Research on Chernobyl Health), and will be covered in the CEREBRAD (Cognitive and Cerebrovascular Effects Induced by Low Dose Ionising Radiation) project. CEREBRAD will address the problem of cerebrovascular effects in humans: in individuals that were exposed in utero, in cohorts of adults from the Chernobyl liquidators, and in children receiving low doses to the brain during cancer radiotherapy. We will study cognitive effects in animal models exposed to radiation at different stages of brain development, with special emphasis on early postnatal exposures, and will examine the initial and late effects induced in brain by irradiation at the cellular and molecular levels.
The main concern of CEREBRAD is to identify the potential risk of doses below 100 mGy delivered to a young child. To inform on risk estimates of the effect from internal and external exposures, as well as synergistic effect with other environmental pollutants, all these different conditions will be evaluated. The consortium is an interdisciplinary team of radiobiologists, epidemiologists, experts in neurodegenerative diseases, genomics, proteomics and bioinformatics, paediatricians and dosimetrists. Special attention will be paid to efficient project management, training, dissemination and communication with stakeholders and the general public.

Coordinator

STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE

Address

Avenue Herrmann Debroux 40
1160 Bruxelles

Belgium

Activity type

Research Organisations

EU Contribution

€ 672 567

Administrative Contact

Nathalie Impens (Dr.)

Participants (11)

ORSZAGOS FREDERIC JOLIOT-CURIE SUGARBIOLOGIAI ES SUGAREGESZSEGUGYI KUTATO INTEZET

Hungary

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 280 500

AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE

Italy

EU Contribution

€ 219 965

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

Germany

EU Contribution

€ 270 000

NEMZETI NEPEGESZSEGUGYI KOZPONT

Hungary

EU Contribution

€ 270 000

UNIVERSITAT ROVIRA I VIRGILI

Spain

EU Contribution

€ 300 000

UPPSALA UNIVERSITET

Sweden

EU Contribution

€ 269 832

STATE INSTITUTION RESEARCH CENTER FOR RADIATION MEDICINE OF THE ACADEMY OF MEDICAL SCIENCES OF UKRAINE

Ukraine

EU Contribution

€ 100 000

ARISTOTELIO PANEPISTIMIO THESSALONIKIS

Greece

EU Contribution

€ 216 852,80

THE UNIVERSITY OF BIRMINGHAM

United Kingdom

EU Contribution

€ 150 000

INSTITUT GUSTAVE ROUSSY

France

EU Contribution

€ 249 800

Project information

Grant agreement ID: 295552

Status

Closed project

  • Start date

    1 October 2011

  • End date

    31 March 2015

Funded under:

FP7-EURATOM-FISSION

  • Overall budget:

    € 4 905 635,40

  • EU contribution

    € 2 999 516,80

Coordinated by:

STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE

Belgium