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Exgenome Molecular Enzymes

Cel

"The main objective of the EXGENOMES project is to develop new and improved thermostable enzymes for use, as reagents, in large-scale DNA synthesis and/or that can act on unnatural components such as in LNA (Locked Nucleic Acids). The target source for the new enzymes is a range of self-replicating mobile genetic elements (phages, plasmids and transposons) from thermophilic bacteria. Increased understanding of self-replication in many mobile genetic elements, such as phi29, has now made the commercial development of new self-priming & strand-displacing polymerases and other enzymes, much more plausible. A number of candidate enzymes, such as a new transposon-coded Thermus DNA polymerase are at hand for this project in the thermophilic bacteria & phage genome bank at Matis.

Nucleic acids based technologies now underpin a large and fast-growing industry, including research, diagnostics and pharmaceutical production. Thermophilic enzymes have played a key role in this development, as polymerases (DNA and RNA), ligases, nucleases, reverse transcriptases, polynucleotide kinases, lysozymes and more, are of great importance in the research industry today. The partner SME´s are all active players in this area from bioprospecting (Prokazyme), laboratory distribution (A&A Biotechnologies), LNA manufacture & diagnostics (Exiqon) to DNA vaccine production (Touchlight Genetics).

Together with the highly competent RTD partners the consortium is well positioned to implement the project according to its goals. The successful development of new thermostable polymerases and other enzymes with the desired properties would have a substantial impact on strengthening the current market status of the SME partners, resulting in growth in income and employment."

Zaproszenie do składania wniosków

FP7-SME-2011
Zobacz inne projekty w ramach tego zaproszenia

System finansowania

BSG-SME - Research for SMEs

Koordynator

PROKAZYME EHF
Adres
Vinlandsleio 14
113 Reykjavik
Islandia
Rodzaj działalności
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Wkład UE
€ 332 749
Kontakt administracyjny
Jakob Kristjansson (Dr.)

Uczestnicy (7)

A&A BIOTECHNOLOGY SC
Polska
Wkład UE
€ 285 840
Adres
Al Zwyciestwa 96/98
84 451 Gdynia
Rodzaj działalności
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt administracyjny
Slawomir Dabrowski (Dr.)
TOUCHLIGHT GENETICS LIMITED
United Kingdom
Wkład UE
€ 154 177
Adres
Queen Anne Street 40
W1G 9EL London
Rodzaj działalności
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt administracyjny
Neil Porter (Dr.)
EXIQON AS
Dania
Wkład UE
€ 143 834
Adres
Bygstubben 9
2950 Vedbaek
Rodzaj działalności
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt administracyjny
Peter Mouritzen (Dr.)
MATIS OHF
Islandia
Adres
Vinlandsleid 12
113 Reykjavik
Rodzaj działalności
Research Organisations
Kontakt administracyjny
Gudmunur Hreggvidsson (Dr.)
UNIWERSYTET GDANSKI
Polska
Adres
Ul. Bazynskiego 8
80309 Gdansk
Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Tadeusz Kaczorowski (Prof.)
INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY
Polska
Adres
Ks. Trojdena 4
02-109 Warsaw
Rodzaj działalności
Research Organisations
Kontakt administracyjny
Janusz Bujnicki (Prof.)
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
Adres
South Kensington Campus Exhibition Road
SW7 2AZ London
Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Tatjana Palalic (Ms.)