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Virtual reality-Treadmill combined Intervention for enhancing Mobility and reducing falls in the Elderly

Objective

Falls are a major public health concern that directly affects millions of elderly Europeans, the healthcare system, and the adult children and caregivers of older people. The V-TIME approach combines cutting edge technology with emerging concepts from gerontology, neuroscience and rehabilitation to reduce fall risk in a unique way. The V-TIME multi-modal intervention consists of treadmill training (TT) that promotes walking abilities and physical fitness. A key novel addition is the simultaneous use of a virtual reality (VR) environment that challenges, implicitly teaches and enhances cognitive skills that facilitate the safe execution of many activities of daily living: visual scanning, planning, dual tasking abilities, and obstacle negotiation.
Exciting pilot studies support the idea that TT augmented with VR (TT+VR) addresses the limitations of existing fall prevention interventions. Via TT+VR, V-TIME offers task-specific training in a motivating and safe environment that can readily be reproduced and standardized. The major goal of the current proposal is to establish the beneficial effects of V-TIME training in a large (n=300) and diverse group of elderly via a multi-centre, prospective randomized controlled trial. Outcomes include post-training 6 month fall incidence rates (the primary outcome), gait, physical activity (e.g. steps walked in 7 days), cognitive function, quality of life, and neuroimaging measures (fNIRS, fMRI). The effects of dosing and an extension phase will be examined (n=60). The consortium brings together world leaders in ageing, neuroscience, rehabilitation and VR technology to test a new therapy that may dramatically reduce the negative costs of falls, financial and other. The RCT is designed to show that V-TIME offers a significant and clinically relevant greater benefit compared to current clinical management; to probe brain plasticity; and to establish efficacy on fall risk, mobility, cognitive function, and functional independence.

Call for proposal

FP7-HEALTH-2011-two-stage
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Coordinator

THE FOUNDATION FOR MEDICAL RESEARCH INFRASTRUCTURAL DEVELOPMENT AND HEALTH SERVICES NEXT TO THE MEDICAL CENTER TEL AVIV
Address
Weizmann Street 6
64239 Tel Aviv
Israel

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Activity type
Research Organisations
Administrative Contact
Hausdorff Jeffrey (Prof.)
EU contribution
€ 1 043 090

Participants (8)

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 680 190
Address
Oude Markt 13
3000 Leuven

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sarah Malevé (Ms.)
UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom
EU contribution
€ 673 469,60
Address
Kings Gate
NE1 7RU Newcastle Upon Tyne

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Helen Gallon (Ms.)
UNIVERSITA DEGLI STUDI DI GENOVA
Italy
EU contribution
€ 685 547
Address
Via Balbi 5
16126 Genova

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Giovanni Luigi Mancardi (Prof.)
STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 963 652
Address
Houtlaan 4
6525 XZ Nijmegen

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maarten Van Langen (Mr.)
UNIVERSITA DEGLI STUDI DI SASSARI
Italy
EU contribution
€ 271 800
Address
Piazza Universita 21
07100 Sassari

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ugo Della Croce (Prof.)
INITION LIMITED
United Kingdom
EU contribution
€ 461 300
Address
Curtain Road 23
EC2A 3LT London

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jeff Ferguson (Mr.)
BEACON TECH LTD
Israel
EU contribution
€ 402 500
Address
Golda Meir St 3
74036 Ness Ziona

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Yoram Lev-Yehudi (Mr.)
ADVANCED DRUG DEVELOPMENT SERVICES - ADDS SRO
Czechia
EU contribution
€ 600 408,20
Address
Jana Uhra 168/10
602 00 Brno

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Andre Aurore (Mr.)