CORDIS
EU research results

CORDIS

English EN

Preparedness, Prediction and Prevention of Emerging Zoonotic Viruses with Pandemic Potential using Multidisciplinary Approaches

Objective

The capacity of zoonotic RNA viruses to emerge as major agents of human disease can appear limitless. Current intervention strategies have demonstrated limited success. Rapid, innovative and effective solutions are needed to reduce the apparently accelerating process of zoonotic disease emergence. We will study the following zoonotic viruses with epidemic potential in Europe: influenza virus, hepatitis E virus, viruses of the Japanese encephalitis serocomplex and lyssaviruses. These diverse viruses arise from the main reservoirs and vectors of potentially emerging viral diseases and use the three major routes of transmission: respiratory, faecal-oral and vector borne. Inter-disciplinary studies will generate valuable data on patterns of crossing the species barrier, transmission and disease emergence, including ecological and anthropological factors which determine virus availability and opportunities for exposure and infection. We will unravel the complex biological interactions between the virus and the recipient hosts that drive the viral adaptation and elucidate the factors determining the ability of the viruses to spread to and between humans (including pandemic spread). Furthermore, immune mechanisms of protection and novel prevention strategies will be investigated. Data will be compiled in a unique and freely accessible data-sharing platform to build a framework for analysing the drivers of pathogen emergence. Modelling, building on the analysis of key data, will focus on the extent to which pathogen trajectories are predictable and will identify high-risk situations and environments. This will allow improvement of disease surveillance, control, preparedness and intervention. Training in leading European Universities, as well as exchanges of approaches and data sharing with national and international health organizations will strengthen European position in this global challenge.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

INSTITUT PASTEUR

Address

Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

France

Activity type

Research Organisations

EU Contribution

€ 3 201 554,22

Administrative Contact

Soizic Sergeant (Mrs.)

Participants (19)

Sort alphabetically

Sort by EU Contribution

Expand all

ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE

Italy

EU Contribution

€ 1 014 017,84

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

EU Contribution

€ 794 361,77

UNIVERSITE D'AIX MARSEILLE

France

EU Contribution

€ 693 772

EIDGENOESSISCHES DEPARTEMENT DES INNERN

Switzerland

EU Contribution

€ 984 745,60

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

EU Contribution

€ 876 316,70

AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL

France

EU Contribution

€ 674 450

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

EU Contribution

€ 344 800

FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA ILLES BALEARS

Spain

EU Contribution

€ 93 706,21

GOETEBORGS UNIVERSITET

Sweden

EU Contribution

€ 483 160

PHILIPPS UNIVERSITAET MARBURG

Germany

EU Contribution

€ 399 900

ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO

Italy

EU Contribution

€ 751 896

THE UNIVERSITY OF EDINBURGH

United Kingdom

EU Contribution

€ 178 141,27

ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO

Italy

EU Contribution

€ 328 943,15

Fondation Health Sciences e-Training

Switzerland

EU Contribution

€ 151 252,25

ISTITUTO SUPERIORE DI SANITA

Italy

EU Contribution

€ 120 000

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA

Italy

EU Contribution

€ 37 500

UNIVERSITAT DE BARCELONA

Spain

EU Contribution

€ 256 034,99

Freunde von GISAID e.V.

Germany

EU Contribution

€ 373 800

EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG

Switzerland

Project information

Grant agreement ID: 278433

Status

Closed project

  • Start date

    1 November 2011

  • End date

    30 April 2017

Funded under:

FP7-HEALTH

  • Overall budget:

    € 15 162 937,16

  • EU contribution

    € 11 758 352

Coordinated by:

INSTITUT PASTEUR

France