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Partner Network for a Clinically Validated Multi-Analyte Lab-on-a-Chip Platform

Objective

The objective of PARCIVAL is to develop an integrated and automated multi-analyte lab-on-a-disk platform for the fast and reliable sample in -> answer out diagnosis of highly infectious respiratory pathogens, resistance patterns and biomarkers for individual severity of the infection. The platform format will be based on completely integrated microfluidic foil-disposables. The disposables will feature different panels (selection of pathogens, resistance patterns, biomarkers), which can be freely selected and combined to allow a comprehensive choice of diagnostic parameters by the clinician at the point-of-care, vastly increasing the access to diagnostic information for doctors in everyday situations and emergencies. The integrated platform with pre-packaged liquid and dry reagents will automate all processing steps from sample preparation, over assay processing up to result reporting.

This will allow evidence-based therapeutic decisions, allow antibiotic prescriptions which are tailored to the individual patient and thus offer the prospect to greatly improve therapeutic outcomes. Also, an air-sampling add-on module for monitoring of clinical ventilation systems will be developed and interfaced to the platform. By acting as early warning system that is able to identify airborne pathogens including resistances, this will increase the impact towards the topic 2.3.1-4 (“retard the development of multi-drug resistance”) as well as the area 2.3.1 (“development of effective infection prevention and control strategies”).

The consortium consists of 9 partners (6 enterprises (4 SMEs), 3 institutes). The project is heavily based on the research capabilities of innovative SMEs. Therefore, SMEs will be the main beneficiaries of exploitation in the project. The key-developments of involved European SMEs will support European companies to establish a leading role in the field lab-on-a-chip applications which is based on the huge in vitro diagnostics market.

Field of science

  • /social sciences/economics and business/business and management/commerce

Call for proposal

FP7-HEALTH-2011-two-stage
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 353 400
Administrative Contact
Willem Van Leeuwen (Prof.)

Participants (8)

HAHN-SCHICKARD-GESELLSCHAFT FUER ANGEWANDTE FORSCHUNG E.v.
Germany
EU contribution
€ 553 750
Address
Wilhelm-schickard-strasse 10
78052 Villingen
Activity type
Research Organisations
Administrative Contact
Saskia Scherer (Ms.)
INSTITUTUL NATIONAL DE CERCETAREDEZVOLTARE PENTRU MICROTEHNOLOGIE
Romania
EU contribution
€ 205 000
Address
Erou Iancu Nicolae Street 32B
077190 Voluntari
Activity type
Research Organisations
Administrative Contact
Carmen Moldovan (Dr.)
MEDIZINISCHES VERSORGUNGZENTRUM DRSTEIN + KOLLEGEN LABORATORIUMSMEDIZIN MIKROBIOLOGIE INFEKTIONSEPIDEMIOLOGIE VIROLOGIE TRANSFUSIONSMEDIZIN
Germany
EU contribution
€ 40 000
Address
Wallstrasse 10
41061 Monchengladbach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lothar Kruska (Dr.)
PATHOFINDER HOLDING BV
Netherlands
EU contribution
€ 420 000
Address
Randwycksingel 45
6229 EG Maastricht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Guus Simons (Dr.)
ROHRER AG WERKZEUG- & MASCHINENBAU
Switzerland
EU contribution
€ 295 400
Address
Bremenstallstrasse 1
4313 Mohlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Hans Peter (Mr.)
Askion GmbH
Germany
EU contribution
€ 400 000
Address
Gewerbepark Keplerstrasse 17-19
07549 Gera
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lutz Doms (Mr.)
AGROBIOGEN GMBH BIOTECHNOLOGIE
Germany
EU contribution
€ 376 000
Address
Larezhausen 2
86567 Hilgertshausen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gottfried Brem (Prof.)
AIRBUS DEFENCE AND SPACE GMBH
Germany
EU contribution
€ 330 000
Address
Willy-messerschmitt-strasse 1
82024 Taufkirchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alois Friedberger (Dr.)