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Identification, homing and monitoring of therapeutic cells for regenerative medicine – Identify, Enrich, Accelerate

Objective

Regenerative medicine focuses on repairing or replacing tissue or organ function lost due to damage or congenital defects using appropriate cells for therapy that have healing capacities like stem cells or progenitor cells. Although regenerative medicine has the potential for more effective therapeutic interventions major improvement in three areas are still needed for a wider establishment of such new concepts in clinical practise: identification of the appropriate cells with healing capacity for the use in therapy, homing of these cells to the damaged tissue, and monitoring of the therapeutic intervention and effect. Thus, a multidisciplinary consortium has set up IDEA, a 60 month collaborative project to develop and establish:
• Photonic methods that allow a contact and marker-free identification and selection of cells with healing capacity for vascular, musculoskeletal and neuronal tissue defects;
• Magnetic cell select devices that capture and transport cells with healing potential through the circulatory system to damaged tissue and organs improving homing;
• Tracer and imaging technologies to monitor the therapeutic effects of interventional regenerative medicine by showing anatomic structure AND demonstrating cellular function using magnetic resonance imaging (MRI) and a new imaging technology known as magnetic particle imaging (MPI).
The IDEA project is intended to provide collaboration between scientists and clinicians from Karolinska Institute (Stockholm, Sweden), Kings College (London, UK), Paracelsus Medical University (Salzburg, Austria) and Julius-Maximilians-University (Würzburg, Germany) together with experts from SMEs specialized in photonic technologies for tissue engineering, medical device manufacturing with extensive experience in regulatory approval, the design, synthesis and up-scaling of nanoparticles for molecular imaging, and regulatory affairs. This multidisciplinary consortium will address scale-up, regulatory work and exploratory clinical investigations using the developed tools, technologies and devices in the time frame of the project.

Call for proposal

FP7-HEALTH-2011-two-stage
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Coordinator

TOPASS GMBH
Address
Drakestrasse 42
12205 Berlin
Germany

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ulrich Pison (Prof.)
EU contribution
€ 708 763,59

Participants (11)

NANOPET PHARMA GMBH
Germany
EU contribution
€ 497 688
Address
Robert-koch-platz 4
10115 Berlin

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nicole Gärtner
CONTRACT MEDICAL INTERNATIONAL SPOL SRO
Czechia
EU contribution
€ 301 394,95
Address
Vazni 848
50003 Hradec Kralove

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Anja Grau (Ms.)
MICROMOD PARTIKELTECHNOLOGIE GMBH
Germany
EU contribution
€ 494 158,88
Address
Friedrich Barnewitz Strasse 4
18119 Rostock

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Joachim Teller (Dr.)
MRB Forschungszentrum fur Magnet-Resonanz-Bayern e.V.

Participation ended

Germany
EU contribution
€ 490 186,70
Address
Am Hubland
97074 Wuerzburg

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Activity type
Research Organisations
Administrative Contact
Peter Jakob (Prof.)
UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT
Germany
EU contribution
€ 763 366,20
Address
Josef-schneider-strasse 2
97080 Wurzburg

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Melanie Bauer (Ms.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 705 412,04
Address
Nobels Vag 5
17177 Stockholm

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maria Von Witting
PARACELSUS MEDIZINISCHE PRIVATUNIVERSITAT SALZBURG - PRIVATSTIFTUNG
Austria
EU contribution
€ 230 955,98
Address
Strubergasse 21
5020 Salzburg

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ludwig Aigner (Prof.)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 594 098,98
Address
Strand
WC2R 2LS London

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Labbett (Mr.)
CELLTOOL GMBH
Germany
EU contribution
€ 801 025,02
Address
Am Neuland 1
82347 Bernried

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Karin Schütze (Dr.)
PROMOTOOL UNTERNEHMENSBERATUNG - DR THOMAS RUESCH
Germany
EU contribution
€ 256 940,80
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Rüsch (Dr.)
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
EU contribution
€ 53 403,86
Address
Hansastrasse 27c
80686 Munchen

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Activity type
Research Organisations
Administrative Contact
Walter Krause (Mr.)