Project description Challenging current Thinking Show the project objective Hide the project objective In this project we aim to investigate the mechanisms involved in memory storage in the brain by a combination of advanced multisite, single unit neural activity monitoring, closed-loop patterned and cell specific activations, and computational techniques, that would allow developing ways to stimulate brain networks in an activity-driven fashion. Combining neuroscience, neuroengineering and computational methods, we intend to create a technological platform for directly interacting with cell assemblies in a two-way dialogue. Using this, we will investigate whether manipulations of cell assembly activities can actually delete or create memories in behavioral experiments. In particular we will concentrate on the hippocampal/cortical interactions in a memory consolidation context as well as on the interactions between two cortical areas, the prefrontal and perirhinal cortex that form a hierarchical representation of memories. The results will provide solid evidence for the role of assemblies in memory processes, and the proof of concept of how these could be manipulated. Eventually these findings should enable radically new research directions for neuro-inspired technologies such as neuromorphic design and cognitive brain-computer interfaces (BCIs) with consequences that we can only begin to imagine. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencescomputer and information sciencescomputational science Programme(s) FP7-ICT - Specific Programme "Cooperation": Information and communication technologies Topic(s) ICT-2011.9.1 - Challenging current Thinking Call for proposal FP7-ICT-2011-C See other projects for this call Funding Scheme CP - Collaborative project (generic) Coordinator KATHOLIEKE UNIVERSITEIT LEUVEN EU contribution € 851 000,00 Address Oude markt 13 3000 Leuven Belgium See on map Region Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven Activity type Higher or Secondary Education Establishments Administrative Contact Sarah Malevé (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITEIT ANTWERPEN Belgium EU contribution € 427 800,00 Address Prinsstraat 13 2000 Antwerpen See on map Region Vlaams Gewest Prov. Antwerpen Arr. Antwerpen Activity type Higher or Secondary Education Establishments Administrative Contact Anne Adams (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data University of Lethbridge Canada EU contribution € 153 900,00 Address 4401 university drive T1K 3M4 Lethbridge See on map Activity type Higher or Secondary Education Establishments Administrative Contact Christine Picken (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 302 144,00 Address Rue michel ange 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Ludovic Hamon (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 358 166,00 Address Houtlaan 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Sabine Vernooij Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITEIT VAN AMSTERDAM Participation ended Netherlands EU contribution € 142 090,00 Address Spui 21 1012WX Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Administrative Contact Allard de Haart (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data