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Control of flowering time by chromatin remodelling

Project information

Grant agreement ID: 298790

Status

Closed project

  • Start date

    16 July 2012

  • End date

    15 July 2014

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 233 705,20

  • EU contribution

    € 233 705,20

Coordinated by:

INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP

Spain

Objective

One of the most exciting aspects of plant science today is how much it contributes to general concepts in biology. The ability to combine a genetic analysis with detailed molecular and biochemical approaches offers real advantages for mechanistic analysis. A fascinating aspect of plant development and an economically very important trait is the switch from vegetative to reproductive development. Flowering time is the most studied developmental transition in plants and our molecular understanding of the genetic pathways regulating flowering time has explained the physiological characteristics that have intrigued biologists for over a century. Many flowering time genetic screens have identified a series of chromatin activities conserved among most complex organisms. The study of this conserved chromatin factors are not only relevant for plant development but for human cells as well because their misregulation is often associated with diseases such as cancer. I propose to study the interplay between SWR1 and NuA4 chromatin remodelling complexes in the control of flowering time. This innovative proposal differs from conventional flowering time studies by using genetic analysis combined with high-resolution chromatin immunoprecipitation experiments and protein complex purification. Collected data will allow comparison with the situation in non-plant systems, which will help the research community to develop a mechanistic consensus model on chromatin regulation in different kingdoms and further broaden our understanding on fundamental cellular processes. Moreover, comprehensive understanding of the fundamentals of flowering time will allow enhancement of crop performance by modulating this trait at the molecular level and will thus be of great value to address the problems of food security that our society will be facing with the postulated global climate changes ahead.
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Coordinator

INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP

Address

Carretera De La Coruna Km7.5
28040 Madrid

Spain

Activity type

Research Organisations

EU Contribution

€ 233 705,20

Administrative Contact

Jose Antonio Jarillo (Dr.)

Project information

Grant agreement ID: 298790

Status

Closed project

  • Start date

    16 July 2012

  • End date

    15 July 2014

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 233 705,20

  • EU contribution

    € 233 705,20

Coordinated by:

INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP

Spain

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