Objetivo Organ transplantation is often the only life saving medical approach for several diseases, in spite of many associated problems (lack of organ donors, rejection, life-long heavy medication). The innovative therapeutic approach of the 21th century is focusing on bioartificial organs as an alternative solution.Tissue engineering and stem cell biology have uncovered groundbreaking opportunities for cellular re-programming, i.e. some cell types can be changed into a pluripotent stem cell (PSC) by over-expressing key transcription factors. These induced pluripotent stem cells (iPSC) share two key characteristics with embryonic stem cells (eSC): self-renewal and pluripotency (ability to differentiate to form any cell type in the human body). Crucially, they are generated from adult cells circumventing many ethical concerns associated with using human eSC. The discovery of human iPSC (hiPSC) enables the growth of an almost unlimited supply of a patient´s own cells, potentially conferring the ability to grow and regenerate tissues and organs from ‘self’, which is expected to resolve organ rejection-related issues. Similarly, recent developments in material science and nanobiotechnology resulted in engineered materials and devices (manipulated and controlled by physical and chemical means), with unique functional or analytical properties. NanoBio4Trans will merge hiPSC-, polymer hybrid scaffolds and biosensor technologies to develop new tools (beyond state-of-the-art) for use in transplantation and biomedical research. The international, trans-sectoral, and multidisciplinary consortium with complementary and leading expertise in material sciences, cell- and molecular biology, sensor technologies, and bioanalytics, aims at developing, optimising and validating a highly vascularised in vivo-like BAL as an extracorporeal bioartificial liver (EBAL), ready to be perfused with human blood plasma, and to be exploited in modern medical technology. Ámbito científico medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencesbiological sciencescell biologymedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinetransplantationmedical and health sciencesmedical biotechnologytissue engineeringbioartificial liver Programa(s) FP7-HEALTH - Specific Programme "Cooperation": Health Tema(s) HEALTH.2012.1.4-2 - Medical technology for transplantation and bioartificial organs Convocatoria de propuestas FP7-HEALTH-2012-INNOVATION-2 Consulte otros proyectos de esta convocatoria Régimen de financiación CP-FP - Small or medium-scale focused research project Coordinador DANMARKS TEKNISKE UNIVERSITET Aportación de la UE € 1 716 653,00 Dirección ANKER ENGELUNDS VEJ 101 2800 Kongens Lyngby Dinamarca Ver en el mapa Región Danmark Hovedstaden Københavns omegn Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Jenny Emneus (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Takara Bio Europe AB Suecia Aportación de la UE € 1 315 690,00 Dirección Arvid Wallgrens backe 413 46 Göteborg Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Karina Lövstedt (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos BIOMODICS APS Dinamarca Aportación de la UE € 578 250,00 Dirección STENGARDS ALLE 31 A 2800 Kgs Lyngby Ver en el mapa Región Danmark Hovedstaden Københavns omegn Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Peter Thomsen (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos LUXCEL BIOSCIENCES LTD Irlanda Aportación de la UE € 1 166 500,00 Dirección BIOTRANSFER UNIT SUITE 3-32 BIOL T12 Cork Ver en el mapa Región Ireland Eastern and Midland Dublin Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Dmitri Papkovsky (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos RIJKSUNIVERSITEIT GRONINGEN Países Bajos Aportación de la UE € 1 191 000,00 Dirección Broerstraat 5 9712CP Groningen Ver en el mapa Región Noord-Nederland Groningen Overig Groningen Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Dick Veldhuis (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos