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Developing an efficient e-infrastructure, standards and data-flow for metabolomics and its interface to biomedical and life science e-infrastructures in Europe and world-wide

Developing an efficient e-infrastructure, standards and data-flow for metabolomics and its interface to biomedical and life science e-infrastructures in Europe and world-wide

Objective

Metabolomics is an important phenotyping technique for molecular biology and medicine. It assesses the molecular state of an organism or collections of organisms through the comprehensive quantitative and qualitative analysis of all small molecules in cells, tissues, and body fluids. Metabolic processes are at the core of physiology. Consequently, metabolomics is ideally suited as a medical tool to characterise disease states in organisms, as a tool to assessment of organism for their suitability in, for example, renewable energy production or for biotechnological applications in general.We now see the emergence of metabolomics databases and repositories in various subareas of metabolomics and the emergence of large general e-infrastructures in the life sciences. In particular the BioMedBridges project is set to link a variety of European Strategy Forum on Research Infrastructures (ESFRI)'s projects, such as ELIXIR and BBMRI.Metabolomics generates large and diverse sets of analytical data and therefore impose significant challenges for the above mentioned e-infrastructures.We will therefore develop policies to ensure that Metabolomics data is
1.\tEncoded in open standards to allow barrier-free and wide-spread analysis.2.\tTagged with a community-agreed, complete set of metadata (minimum information standard).3.\tSupported by a communally developed set of open source data management and capturing tools.4.\tDisseminated in open-access databases adhering to the above standards.5.\tSupported by vendors and publishers, who require deposition upon publication6.\tProperly interfaced with data in other biomedical and life-science e-infrastructures (such as ELIXIR, BioMedBridges, EU-Openscreen).
In order to achieve this, we have assembled the COSMOS (CCOordination of Standards in MetabOlomicS) consortium of leading European groups in Metabolomics and we will interface with all interested players in Metabolomics world-wide in the Metabolomics community and beyond.
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Coordinator

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Address

Meyerhofstrasse 1
69117 Heidelberg

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 562 794

Administrative Contact

Jillian Rowe (Ms.)

Participants (15)

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LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE

Germany

EU Contribution

€ 154 829

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

EU Contribution

€ 139 100

Steno Diabetes Center A/S

Denmark

EU Contribution

€ 50 321

UNIVERSITAT DE BARCELONA

Spain

EU Contribution

€ 124 334

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Finland

EU Contribution

€ 39 987

UNIVERSITE VICTOR SEGALEN BORDEAUX II

France

EU Contribution

€ 74 900

CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE

Italy

EU Contribution

€ 101 008

UNIVERSITEIT LEIDEN

Netherlands

EU Contribution

€ 215 177

NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO

Netherlands

EU Contribution

€ 19 474

MEDICAL RESEARCH COUNCIL

United Kingdom

EU Contribution

€ 76 184

THE UNIVERSITY OF MANCHESTER

United Kingdom

EU Contribution

€ 97 370

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

EU Contribution

€ 71 048

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

United Kingdom

EU Contribution

€ 103 148

THE UNIVERSITY OF BIRMINGHAM

United Kingdom

EU Contribution

€ 108 926

UNIVERSITA DEGLI STUDI DI FIRENZE

Italy

EU Contribution

€ 21 400

Project information

Grant agreement ID: 312941

Status

Closed project

  • Start date

    1 October 2012

  • End date

    30 September 2015

Funded under:

FP7-INFRASTRUCTURES

  • Overall budget:

    € 2 624 011

  • EU contribution

    € 1 960 000

Coordinated by:

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany