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Towards Tissue Engineering Solutions for Cardiovascular Surgery

Objective

The aim of the TECAS ITN is to integrate the major European contributors in the field of cardiovascular tissue engineering (TE) and regenerative medicine (RM), to generate a coherent framework of expertise which will facilitate the training and career development of early stage researchers (ESRs) in the field. In particular, the intention of this ITN is to focus on the clinical needs of cardiac valve replacement/repair, myocardium reconstruction and patch graft angioplasty of the great blood vessels, with a view to developing the underpinning expertise and technology that will be required to manufacture functional TE cardiovascular implants for clinical use in the near future. The TECAS ITN supports and transfers novel crossdisciplinary and intersectorial training to junior researchers, which is critical to the long-term sustainability of the cardiovascular implant research and industry in Europe, enhancing its competitiveness against the North American sector. The goal of this ITN is to consolidate the extensive multidisciplinary experience in training and research of its academic, clinical and industrial Partners to train the new generation of competent and balanced clinicians, scientists, and engineers, who currently are in great demand by the medical devices industry and clinical sector. This goal will be facilitated through the research projects of the Network which span over the intersectorial innovation pipeline of a number of TE products and technologies from basic science to translational research and beyond. The strategy of the TECAS ITN involves the use of functionalised 3D scaffolds, which have been seeded with either differentiated stromal cells or adult mesenchymal stem cells derived from the intended recipient, and either physically conditioned in the laboratory in bioreactors, with a view to producing biological and biomechanical functionality of the graft prior to implantation, or used unseeded with a view to attracting endogenous cell colonisation after implantation.

Call for proposal

FP7-PEOPLE-2012-ITN
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Coordinator

MEDIZINISCHE HOCHSCHULE HANNOVER
Address
Carl-neuberg-strasse 1
30625 Hannover
Germany

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Frank Dittrich (Mr.)
EU contribution
€ 667 127,50

Participants (6)

HAVERICH DR.AXEL, MEYER-KOBBE, DR.CLEMENS GBR

Participation ended

Germany
Address
Feodor Lynen Strasse 23
30625 Hannover

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Harder (Dr.)
UNIVERSITAETSKLINIKUM AACHEN
Germany
EU contribution
€ 446 887,76
Address
Pauwelsstrasse 30
52074 Aachen

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Volker Legewie (Mr.)
CORLIFE OHG
Germany
EU contribution
€ 222 068,88
Address
Feodor Lynen Strasse 23
30625 Hannover

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Harder (Dr.)
TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
EU contribution
€ 609 906,34
Address
Groene Loper 3
5612 AE Eindhoven

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
A J H M Peels (Dr.)
UNIVERSITA DEGLI STUDI DI PADOVA
Italy
EU contribution
€ 725 263,88
Address
Via 8 Febbraio 2
35122 Padova

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rosa Maria Campagna (Dr.)
PANEPISTIMIO PATRON
Greece
EU contribution
€ 668 956,64
Address
University Campus Rio Patras
265 04 Rio Patras

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dimosthenis Mavrilas (Prof.)