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Joint training and research network on Chromatin Dynamics and the DNA Damage Response

Objective

DNA is tightly wrapped around histones to form chromatin, a highly dynamic structure that can adopt different conformations with contrasting degrees of compaction. Essential processes of DNA metabolism, such as DNA repair, replication or transcription operate in the context of chromatin and higher order chromosomal organization. Understanding how modulation of chromatin structure and repair influence cell fate decisions in development and disease or how genome surveillance factors interact with the chromatin structure to safeguard the genome is an emerging question that represents a major challenge for human health. The objectives of the aDDRess ITN are: 1. to establish a European research platform of excellence in the proposed field, 2. to create a Network dedicated for the training of ESR/ERs promoting their independent careers and prospects and 3. to transform our current collaborations into a stronger intellectual and training network with links to the industry. In addressing these aims, we have put forward a multidisciplinary approach to study this central thematic area at the molecular, cellular and systems level by assembling a group of scientists with cross disciplinary expertise and capabilities. This integrated approach is likely to provide a solid groundwork on genome maintenance and chromatin dynamics driven by DNA damage.

Field of science

  • /natural sciences/biological sciences/genetics and heredity/genome

Call for proposal

FP7-PEOPLE-2012-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

IDRYMA TECHNOLOGIAS KAI EREVNAS
Address
N Plastira Str 100
70013 Irakleio
Greece
Activity type
Research Organisations
EU contribution
€ 580 516,86
Administrative Contact
Zinovia Papatheodorou (Mrs.)

Participants (9)

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 689 029,66
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Riet Van Zeijl (Mrs.)
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 293 379,46
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ivan Kristoffersen (Mr.)
UNIVERSITAET ZU KOELN
Germany
EU contribution
€ 230 868,88
Address
Albertus Magnus Platz
50931 Koeln
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christian Klar (Dr.)
CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
France
EU contribution
€ 529 497,32
Address
Rue Laurent Fries 1
67404 Illkirch Graffenstaden
Activity type
Research Organisations
Administrative Contact
Steve Brooks (Dr.)
IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE
Italy
EU contribution
€ 492 125,92
Address
Via Adamello 16
20139 Milano
Activity type
Research Organisations
Administrative Contact
Carlo Raimondi Cominesi (Mr.)
FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III
Spain
EU contribution
€ 235 481,62
Address
Calle Melchor Fernandez Almagro 3
28029 Madrid
Activity type
Research Organisations
Administrative Contact
Dolores Liebanes (Dr.)
UNIVERSITY OF DUNDEE
United Kingdom
EU contribution
€ 293 856,64
Address
Nethergate
DD1 4HN Dundee
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Zoe Kidd (Mrs.)
BIOMEDCODE ELLAS ANONIMI ETERIA EPISTIMONIKIS KAI TEXNOLOGIKIS EREVNAS KAI EMBORIKIS EKMETALLEFSIS EPHARMOGON IATRIKIS
Greece
EU contribution
€ 229 768,88
Address
Alexander Fleming Street 34
16672 Vari
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Maria Denis (Dr.)
ATLAS BIOLABS GMBH
Germany
EU contribution
€ 229 768,88
Address
Kerpener Strasse 61-69
50937 Koln
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Karsten Heidtke (Dr.)