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Genes And Proteins for AutoImmunity Diagnostics

Objective

"Rheumatoid arthritis (RA) and sistemic lupus erythematosus (SLE) are two autoimmune diseases that respectively affect an estimated population of 1.537.000 and 1.272.000 of patients in Europe. Such diseases show a long prodrome during which there are no clinical symptoms. In some cases, therapeutic treatments have been developed to improve patients quality of life. Therefore, reliable diagnostic/prognostic tools are necessary not only for an early diagnosis and for monitoring disease activity, but also for setting up personalized therapeutic treatments.
The clinical diagnosis of RA and SLE is assisted by the use of in vitro diagnostic tests aimed at the evaluation of the presence/level of few autoantibodies circulating in serum. Yet, this diagnostic approach is unsatisfactory because it can assist the diagnosis only after the first disease onset, it is not useful to evaluate the disease susceptibility for an early prevention, and it does not provide information to follow the disease progression for the set up of personalized therapeutic treatments.
To solve these drawbacks, the GAPAID project is aimed at supplying the SME participants of the scientific and technological activities necessary to develop a novel diagnostic / prognostic platform for patients affected by RA and SLE. To this aim the scientific activities will be focused on the discovery of the diagnostic and prognostic value of the genetic and serological profiles associated to RA and SLE. The technological activities will contribute to develop multiplex arrays for the contemporary detection of more analytes and to set up a software for the RA and SLE diagnosis / prognosis by matching the clinical, genetic, and serological data. The exploitation of the scientific and technological results will allow the SME participants to the GAPAID proposal to develop and to further commercialize both for RA and SLE an in vitro diagnostic product composed by a genetic array, a serological array, and a software."

Call for proposal

FP7-SME-2012
See other projects for this call

Coordinator

TOSCANA BIOMARKERS S.R.L
Address
Via Fiorentina 1
53100 Siena
Italy
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 181 015,82
Administrative Contact
Maria Claudia Alcaro (Dr.)

Participants (9)

PROGENIKA BIOPHARMA SA
Spain
EU contribution
€ 581 507,61
Address
Parque Ibaizabal Bidea Edificio 504 Parque Tecnologico Derio
48160 Vizcaya Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Sergio Escorza (Dr.)
DIAGNOSTICUM GYARTO ES FORGALMAZO ZARTKORUEN MUKODO RESZVENYTARSASAG
Hungary
EU contribution
€ 194 371,32
Address
Attila U 126
1047 Budapest
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ferenc Péterfy (Dr.)
UNIVERSITA DI PISA
Italy
EU contribution
€ 13 472
Address
Lungarno Pacinotti 43/44
56126 Pisa
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paola Migliorini (Prof.)
UNIVERSITA DEGLI STUDI DI FIRENZE
Italy
Address
Piazza San Marco 4
50121 Florence
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paolo Rovero (Prof.)
UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA
Spain
Address
Barrio Sarriena S N
48940 Leioa
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Charo Sánchez
OMNILAB IBERIA SL
Spain
EU contribution
€ 30 586
Address
Calle Rios Rosas 11 Escalera A 11
28003 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alfredo Benés (Mr.)
EOTVOS LORAND TUDOMANYEGYETEM
Hungary
Address
Egyetem Ter 1-3
1053 Budapest
Activity type
Higher or Secondary Education Establishments
Administrative Contact
József Prechl (Dr.)
PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS
Hungary
Address
Vasvari Pal Utca 4
7622 Pecs
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eva Somosi
Pharma Quality Europe S.R.L.
Italy
EU contribution
€ 209 047,25
Address
Via Brunetto Degli Innocenti 2
50063 Figline Valdarno
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mariola Mier (Dr.)