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Training network for developing innovative (bio)artificial devices for treatment of kidney and liver disease

Objective

Renal and liver diseases are global public health problems, with the incidences of end-stage renal disease (ESRD) and end-stage liver disease (ESLD) rising annually. Due to the lack of donor kidneys, most of ESRD patients depend on dialysis treatment using either an artificial kidney or the peritoneal membrane. Both modes are inefficient in removing uremic waste molecules and inadequately remove excess body fluids, potassium and phosphate contributing significantly to severe patient health problems, poor life quality and high mortality (15-20% per year). The impairment of liver functions has also serious implications and it is responsible for high rates of patient morbidity and mortality. Presently, liver transplantation remains the treatment of choice for ESLD patients but it is limited by both the high costs and severe shortage of donor organs. BIOART ITN will provide state-of-the-art multidisciplinary training for a cohort of 16 young researchers in order to equip them with the skills required to make a significant impact in the treatment of kidney and liver diseases. For this, BIOART ITN will develop:

- A prototype artificial kidney devices enabling prolonged / continuous removal of uremic toxins
- A prototype bioartificial kidney device that utilizes human renal epithelial cells for removal of uremic toxins.
- Prototype bioreactor devices to ensure viability and functions of hepatocyte cells.

In fact, BIOART ITN will provide the European Union with specific multidisciplinary expertise in the area of (bio)artificial organs for treatment of kidney and liver diseases. This will be achieved through the training of highly educated researchers able to understand and eventually to manage all scientific, industrial and clinical aspects of these (bio)artificial organs. Fourteen individual RTD Projects will be performed and thirty five scientific training courses will be offered by the host organizations to the recruited young researchers. During four years, the re

Call for proposal

FP7-PEOPLE-2012-ITN
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Coordinator

UNIVERSITEIT TWENTE
Address
Drienerlolaan 5
7522 NB Enschede
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 881 010,49
Administrative Contact
Ferdinand Damhuis (Mr.)

Participants (10)

UNIVERSITE PAUL SABATIER TOULOUSE III
France
EU contribution
€ 255 948,66
Address
Route De Narbonne 118
31062 Toulouse Cedex 9
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Carole Matthia (Mrs.)
STICHTING RADBOUD UNIVERSITEIT

Participation ended

Netherlands
EU contribution
€ 251 670,43
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maarten Van Langen (Mr.)
UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE
France
EU contribution
€ 367 445,43
Address
Rue Du Docteur Schweitzer Cs 60319 Centre Pierre Guillaumat
60203 Compiegne Cedex
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Damien Baratte (Mr.)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 484 975,92
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Administrative Contact
Loredana De Bartolo (Dr.)
UNIVERSITAET LEIPZIG
Germany
EU contribution
€ 447 437,76
Address
Ritterstrasse 26
04109 Leipzig
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Doris Stefanowa (Dr.)
UNIVERSITA DELLA CALABRIA
Italy
EU contribution
€ 240 837,96
Address
Via Pietro Bucci 7/11/B
87036 Arcavacata Di Rende
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Efrem Curcio (Dr.)
EXCORLAB GMBH
Germany
EU contribution
€ 286 201,08
Address
Glanzstoffstrasse Industriecenter
63785 Obernburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Horst-Dieter Lemke (Dr.)
GVS SPA
Italy
EU contribution
€ 208 635,24
Address
Via Roma 50
40069 Zola Predosa
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Soccorso Gaeta (Dr.)
Bionethos Innovation GmbH
Germany
EU contribution
€ 143 100,54
Address
Krankenhausstrasse 7
04668 Parthenstein-klinga
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Cornelia Matejko (Ms.)
UNIVERSITEIT UTRECHT
Netherlands
EU contribution
€ 225 352,49
Address
Heidelberglaan 8
3584 CS Utrecht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jos Lieffering