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Quantitative T cell Immunology

Objective

The primary objective of this ITN is to train a new generation of European quantitative immunologists, who will be able to address challenges arising in Systems Immunology. This will be achieved with the proposed Network, Quantitative T cell Immunology (QuanTI), that will train 11 ESRs and 4 ERs, bringing together renowned experimental and theoretical scientists from private and academic institutions.

Health and disease are regulated, to a large extent, by our immune system. A quantitative approach to Immunology must not only integrate a wide range of biological data but also increase our understanding of immunological processes at all levels of organisation. This will be achieved by exploiting state-of-the-art knowledge and technology of the academic and industrial partners. The scientific programme of the proposed Network consists of 6 research work packages and focuses on one of the current challenges in Systems Immunology: the dynamics of T cells in the periphery. Specifically the Network aims to provide a coherent multi-scale framework to: (i) the establishment and diversity of the T cell pool in the periphery, and (ii) the differentiation programme of T cell populations during adaptive immune responses. Synthesising models and immunological data poses a challenge that cannot be successfully managed by immunologists, mathematicians, computer scientists or physicists on their own. QuanTI will provide an excellent multi-disciplinary and inter-sectorial research environment to train a new generation of quantitative immunologists.

The propose ITN will strongly advance the development of new quantitative concepts to characterise, and therapeutically modify, immune responses. In a wider context, QuanTI provides a model for a new, hands-on inter-disciplinary and inter-sectorial training programme in biomedical sciences that will catalyse the progress from a qualitative, molecule-oriented approach to a quantitative, systems-level research strategy.

Field of science

  • /medical and health sciences/basic medicine/immunology

Call for proposal

FP7-PEOPLE-2012-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITY OF LEEDS
Address
Woodhouse Lane
LS2 9JT Leeds
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 980 695,97
Administrative Contact
Martin Hamilton (Mr.)

Participants (11)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 287 256,64
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tatjana Palalic (Ms.)
UNIVERSITEIT UTRECHT
Netherlands
EU contribution
€ 207 056,74
Address
Heidelberglaan 8
3584 CS Utrecht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Nasrin Vaziry (Ms.)
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 239 061,46
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jam Borghans (Dr.)
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands
EU contribution
€ 239 061,46
Address
Plesmanlaan 121
1066 CX Amsterdam
Activity type
Research Organisations
Administrative Contact
Reneske De Jong (Ms.)
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
EU contribution
€ 224 268,88
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Activity type
Research Organisations
Administrative Contact
Ina Krischek (Dr.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 224 268,88
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Anja Stielow (Ms.)
INSTITUT PASTEUR
France
EU contribution
€ 225 193,54
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Activity type
Research Organisations
Administrative Contact
Marie-Laure Rosso (Dr.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 225 193,54
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
Teva West (Mr.)
NATIONAL UNIVERSITY OF IRELAND MAYNOOTH
Ireland
EU contribution
€ 495 128,92
Address
Co Kildare
W23 Maynooth
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ken Duffy (Dr.)
NATIONAL UNIVERSITY OF IRELAND GALWAY
Ireland
EU contribution
€ 247 014,46
Address
University Road
H91 Galway
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mari Vahey (Ms.)
BAYER TECHNOLOGY SERVICES GMBH
Germany
EU contribution
€ 418 369,60
Address
Kaiser-wilhelm-allee
51373 Leverkusen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Peter Steudtner