CORDIS
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CORDIS

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Micro/nanosensors for early cancer warning system - diagnostic and prognostic information

Project information

Grant agreement ID: 318053

Status

Closed project

  • Start date

    1 January 2013

  • End date

    31 December 2016

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 584 800

  • EU contribution

    € 584 800

Coordinated by:

INSTITUTE OF TECHNOLOGY TALLAGHT

Ireland

Objective

"Oncologists still rely heavily on biological characterisation of tumours and a limited number of biomarkers which have demonstrated clinical utility. Routine cancer diagnostic tools may not be always sensitive enough and may only detect proteins at levels corresponding to an advanced stage of the disease. Recently, new genomic and proteomic molecular tools (molecular signatures) are being employed which include genetic and epigenetic signatures, changes in gene expression, protein profiles and post-translational modification of proteins. Such advanced diagnostic tools are not always readily adapted to clinical cancer screening due to their complexity, costs and the requirement for highly-qualified operators. Novel bioanalytical methodologies for detection of specific biomarkers/ biomolecules, based on nanostructured electronic sensors (rapid, sensitive devices capable of miniaturisation and deployment on site or in small clinics), fulfill the necessary requirements and have the potential to compliment time- and labour consuming clinical analysers used in medical laboratories currently. The primary objective of this proposal, therefore, is to gather together an international and interdisciplinary consortium of ten research teams from EU Member States, Third (including ENP) countries with EU agreements on S&T, in order to share and jointly exploit knowledge and expertise in the development of micro/nanosensors as tools in early cancer diagnosis. A key scientific target is the realisation of intelligent electronic devices which respond to biomolecules such as formaldehyde, amines, metal ions, saccharides, activities of amine oxidases, arginase and glutathione-S-transferase. This will entail design, development and characterisation of nano-scale transducers suitable for testing in clinical samples."

Coordinator

INSTITUTE OF TECHNOLOGY TALLAGHT

Address

Old Blessington Road
24 Tallaght Dublin 24

Ireland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 85 800

Administrative Contact

Eithne Dempsey (Prof.)

Participants (5)

UNIVERSITATEA DIN BUCURESTI

Romania

EU Contribution

€ 117 000

UNIVERSITAT ROVIRA I VIRGILI

Spain

EU Contribution

€ 87 000

UNIVERSIDADE DE COIMBRA

Portugal

EU Contribution

€ 87 700

LINKOPINGS UNIVERSITET

Sweden

EU Contribution

€ 108 400

UNIVERSITE LYON 1 CLAUDE BERNARD

France

EU Contribution

€ 98 900

Project information

Grant agreement ID: 318053

Status

Closed project

  • Start date

    1 January 2013

  • End date

    31 December 2016

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 584 800

  • EU contribution

    € 584 800

Coordinated by:

INSTITUTE OF TECHNOLOGY TALLAGHT

Ireland