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Benznidazol and Triazol REsearch group for Nanomedicine and Innovation on Chagas diseasE

Objective

The BERENICE consortium is aiming at providing a new and cost-effective solution to a better treatment for Chagas chronic patients. Please see its objectives below :

Main objective
• Obtain a more effective, better tolerated and cheaper formulation of a drug with trypanocidal activity to cure Chagas disease

Specific Objectives
• Obtain results of pharmacokinetics of new formulations
• Assess trypanocidal activity of new formulations in vitro and in animal model
• Involve partners, research and industry in endemic countries to promote technology transfer and promote in-site solutions at cheaper cost.
The foreseen results of this project would have firstly an impact on the better comprehension and control of the SUVs behavior as drug delivery nanodevices for the specific APIs to be conjugated. If this conjugation is successful, further impacts are expected dealing with technology transfer issues, such as scale-up of the corresponding SUVs preparation methodology and its implementation at industrial scale.
Apart from including stong participation from endemic countries's institutions, the consortium also involves private companies, thus enabling the participation of all the key actors of the chain to confront and control better Chagas disease. The innovative approach, through the new developed nano- and microparticles based formulations will have an important impact on the safety of the medicament since the therapeutic efficacy will increase and consequently the doses needed and the incidences caused by adverse effects will be reduced.

Call for proposal

FP7-HEALTH-2012-INNOVATION-1
See other projects for this call

Coordinator

INSTITUT CATALA DE LA SALUT
Address
Gran Via De Les Corts Catalanes 587
08007 Barcelona
Spain
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
EU contribution
€ 1 092 805,17
Administrative Contact
Joan X. Comella (Dr.)

Participants (10)

INSTITUTO DE HIGIENE E MEDICINA TROPICAL

Participation ended

Portugal
Address
Rua Da Junqueira 100
1349-008 Lisboa
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marcelo Sousa Silva (Dr.)
CENTRO DE INVESTIGACION BIOMEDICA EN RED BIOINGENIERIA, BIOMATERIALES Y NANOMEDICINA

Participation ended

Spain
EU contribution
€ 456 627,20
Address
Calle Poeta Mariano Esquillor
50018 Zaragoza
Activity type
Research Organisations
Administrative Contact
Jesús Izco (Dr.)
CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.
Spain
EU contribution
€ 100 518,75
Address
Calle Monforte De Lemos 5
28029 Madrid
Activity type
Research Organisations
Administrative Contact
Jesús Izco (Dr.)
FUNDACAO OSWALDO CRUZ
Brazil
EU contribution
€ 374 638
Address
Avenida Brasil 4365
21040 900 Rio De Janeiro
Activity type
Research Organisations
Administrative Contact
Rodrigo Corrêa-Oliveira (Prof.)
UNIVERSIDADE NOVA DE LISBOA
Portugal
EU contribution
€ 280 000
Address
Campus De Campolide
1099 085 Lisboa
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marcelo Sousa Silva (Dr.)
ADMINISTRACION NACIONAL DE LABORATORIOS E INSTITUTOS DE SALUD DR. CARLOS G. MALBRAN
Argentina
EU contribution
€ 173 147,83
Address
Avenida Velez Sarsfield 563
1281 Buenos Aires
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Ezequiel Cravero (Mr.)
UNIVERSITAT DE BARCELONA
Spain
EU contribution
€ 250 999,92
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Xavier Gutierrez (Mr.)
PRAXIS PHARMACEUTICAL FRANCE SARL
France
EU contribution
€ 71 677,83
Address
Avenue Paul Doumer 147
92500 Rueil Malmaison
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pinhas Melul (Mr.)
LABORATORIO ELEA SOCIEDAD ANONIMA COMERCIAL, INDUSTRIAL, FINANCIERA Y AGROPECUARIA
Argentina
EU contribution
€ 75 230,53
Address
Sanabria 2353
C1417AZE Buenos Aires
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Luis Ferrero (Mr.)
BIOKERALTY RESEARCH INSTITUTE AIE
Spain
EU contribution
€ 122 571,77
Address
Entidad Arcaute 005 Arcaute
01192 Arcaute Alava
Activity type
Other
Administrative Contact
Angel Del Pozo (Dr.)