CORDIS
EU research results

CORDIS

English EN

“MycoBiotics” as a new technology platform for the treatment of human respiratory and genital tract diseases

Project information

Grant agreement ID: 335010

Status

Closed project

  • Start date

    1 July 2013

  • End date

    31 December 2014

Funded under:

FP7-IDEAS-ERC

  • Overall budget:

    € 165 429,91

  • EU contribution

    € 150 000

Hosted by:

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

Objective

The use of Mycoplasma pneumoniae or its closest relative M. genitalium engineered for the controlled delivery of therapeutic peptides or proteins in situ, i.e. where they currently reside, could open new possibilities for the treatment of lung and genital tract diseases.
Taking advantage of the parasite nature of M. pneumoniae to lung tissue, we plan to use genetically engineered forms of this bacterium for the local, and eventually conditional delivery of therapeutic proteins in the context of distinct and many times highly invalidating respiratory disorders, as a proof-of-concept of a new technology platform.
Results of the work done at the CRG on the two projects above shall be validated in vitro and in vivo and, if successful, constitute the basis for a licensing agreement, or eventually a spin-off company created to bring the engineered bacteria or modifications thereof into the clinic. Interestingly, additional applications could be proposed at some point to diseases of the genital tract using engineered M. genitalium as a living vector.

Host institution

FUNDACIO CENTRE DE REGULACIO GENOMICA

Address

Carrer Doctor Aiguader 88
08003 Barcelona

Spain

Activity type

Research Organisations

EU Contribution

€ 150 000

Administrative Contact

Stefan Pönisch (Mr.)

Beneficiaries (1)

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 150 000

Project information

Grant agreement ID: 335010

Status

Closed project

  • Start date

    1 July 2013

  • End date

    31 December 2014

Funded under:

FP7-IDEAS-ERC

  • Overall budget:

    € 165 429,91

  • EU contribution

    € 150 000

Hosted by:

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain