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BBMRI - Large Prospective Cohorts

Objective

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, and the actual comparability of selected patients. Large prospective cohort (LPC) studies following up initially healthy participants for years or decades are considered more reliable and different diseases can be studied. LPC studies require large numbers of subjects which are costly but particularly benefited from the advent of high throughput techniques providing opportunities for powerful study designs. This project unites the large study sets of the European Biobanking and Biomolecular Research Infrastructure (BBMRI) and the International Agency for Research on Cancer (IARC), thus achieving a worldwide unique scale of integration. Specifically, we aim to:1)Evaluate/improve the harmonization of individual data on health, lifestyle and other exposures;2)Develop/implement harmonized definitions of diseases;3)Improve biobanking and research technologies and develop innovative solutions facilitating high-quality, fair access to samples and data;4)Provide free transnational access by users, through study proposals selected by an open, pan-European call;5)In the framework of these studies, generate and provide access to whole genome sequences, transcriptome, proteome, metabolome and methylome data;6)Build new public-private partnerships involving large-scale prospective cohorts, and strengthening existing ones, allowing transparent industrial access to academic expertise;7) Build a network transferring the expertise of established European large-scale biobanks to new biobank initiatives under development in other countries.
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Coordinator

HELSINGIN YLIOPISTO

Address

Yliopistonkatu 3
00014 Helsingin Yliopisto

Finland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 956 508,78

Administrative Contact

Birgit Simell (Dr.)

Participants (33)

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ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU Contribution

€ 288 681,60

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER

France

EU Contribution

€ 916 160,23

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

EU Contribution

€ 460 484,58

MEDIZINISCHE UNIVERSITAT GRAZ

Austria

EU Contribution

€ 284 748,40

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 204 019,31

GENOME RESEARCH LIMITED

United Kingdom

EU Contribution

€ 236 303,60

ACADEMISCH ZIEKENHUIS GRONINGEN

Netherlands

EU Contribution

€ 164 077,22

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

Germany

EU Contribution

€ 838 896

NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU

Norway

EU Contribution

€ 269 816,17

TARTU ULIKOOL

Estonia

EU Contribution

€ 465 427,31

UPPSALA UNIVERSITET

Sweden

EU Contribution

€ 512 575,94

FUNDACIO PARC CIENTIFIC DE BARCELONA

Spain

EU Contribution

€ 1 528,21

CAMBRIDGE PROTEIN ARRAYS LTD

United Kingdom

EU Contribution

€ 284 466

PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS

Hungary

EU Contribution

€ 47 561,50

UNIVERSITY OF LEICESTER

United Kingdom

The Research Institute of the Mc Gill University Health Centre

Canada

EU Contribution

€ 147 840

LEGAL PATHWAYS BV

Netherlands

EU Contribution

€ 62 809

ISLENSK ERFDAGREINING EHF

Iceland

EU Contribution

€ 55 800,50

TERVEYDEN JA HYVINVOINNIN LAITOS

Finland

EU Contribution

€ 221 556,97

INTERNATIONAL PREVENTION RESEARCH INSTITUT-IPRI MANAGEMENT

France

EU Contribution

€ 41 195

LATVIJAS BIOMEDICINAS PETIJUMU UN STUDIJU CENTRS

Latvia

EU Contribution

€ 47 561,50

SVEUCILISTE U SPLITU

Croatia

EU Contribution

€ 47 561,50

WROCLAWSKIE CENTRUM BADAN EIT+ SPZOO

Poland

EU Contribution

€ 47 561,50

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Germany

EU Contribution

€ 443 656,17

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 245 966,31

VAN VEEN EVERT BERNARD

Netherlands

EU Contribution

€ 56 372,95

UNIVERSITEIT MAASTRICHT

Netherlands

EU Contribution

€ 41 195,76

FOLKEHELSEINSTITUTTET

Norway

EU Contribution

€ 41 195,76

STATENS SERUM INSTITUT

Denmark

EU Contribution

€ 108 090,17

UNIVERSITY OF BRISTOL

United Kingdom

EU Contribution

€ 156 182,07

BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC)

Austria

EU Contribution

€ 14 552

UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA

Italy

EU Contribution

€ 4 922

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 284 725,99

Project information

Grant agreement ID: 313010

Status

Closed project

  • Start date

    1 February 2013

  • End date

    31 October 2017

Funded under:

FP7-INFRASTRUCTURES

  • Overall budget:

    € 10 604 623,39

  • EU contribution

    € 8 000 000

Coordinated by:

HELSINGIN YLIOPISTO

Finland