Final Report Summary - NEURO-COMM (Inter-areal cortical communication: investigating the relationship between hemodynamic and electrophysiological measurements)
A large part of the cerebral processes associated with our actions or out thoughts is implemented through the communication between different groups of neurons located in distant brain regions. With this project, we aimed to more deeply understand processes of neuronal communications that are ongoing when we perform a task or when we are at rest. To reach this goal, we developed new technologies to record simultaneously high-density electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) data, to remove signals of non-neuronal origin mixed in the data, and perform accurate reconstructions of brain activity. The direct comparison between long-range functional interactions in the brain estimated from EEG and fMRI data has started shedding new light on how different parts of the brain exchange information. In conclusion, the project has provided new fundamental knowledge about long-range functional interactions in the human brain. This may open up new avenues to understand the physiological basis of functional connectivity alterations in several brain diseases. Following these research achievements, the researcher has been able to establish himself as a prominent figure in the field of systems neuroscience, and this has enabled his long-term career integration in the EU.