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Inter-areal cortical communication: investigating the relationship between hemodynamic and electrophysiological measurements

Ziel

"Perception, cognition and behaviour are achieved through the coordination of multiple brain regions, which exchange information between each other. Large-scale functional interactions arise at two distinct but potentially related temporal scales: “slow” hemodynamic fluctuations measured with functional magnetic resonance imaging (fMRI); and “fast” electrophysiological oscillations of the neurons, as measured non-invasively by electroencephalography (EEG) and magnetoencephalography, and invasively at finer spatial scales by local field potentials and multi-unit activity. Despite enormous recent progress, our understanding of the relationship between, and functional role of fast and slow synchronization in inter-areal cortical communication is still limited. In this project, we will study interactions in large-scale functional networks of healthy human volunteers using combined electrophysiological and hemodynamic measures. We will characterize functional brain networks showing coherent hemodynamic activity at rest and examine how the functional architecture of these networks varies with active behaviour. Moreover, we will study large-scale interactions at different spatio-temporal scales, relating slow fMRI fluctuations with fast EEG oscillations recorded simultaneously. Finally, we will target specific areas under different states by transcranial magnetic stimulation to investigate the causal effects of these focal perturbations on the spatial and temporal properties of brain networks. These studies will provide deeper insights into the mechanisms underlying inter-areal cortical communication and their functional role with respect to behaviour."

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2012-CIG
Andere Projekte für diesen Aufruf anzeigen

Koordinator

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
EU-Beitrag
€ 100 000,00
Adresse
Raemistrasse 101
8092 Zuerich
Schweiz

Auf der Karte ansehen

Region
Schweiz/Suisse/Svizzera Zürich Zürich
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Nicole Wenderoth (Prof.)
Links
Gesamtkosten
Keine Daten