Description du projet FET Young Explorers Afficher les objectifs du projet Masquer les objectifs du projet RiboNets aims at programming cellular networks and community behaviour using newly engineered logical gates that transmit and process information within cells in an innovative way, namely via RNA-based devices.RiboNets wants to develop a newly designed RNA-based toolbox for cellular computing. RNA has three major advantages: (a) RNA turnover is fast thus efficient computing is possible with RNA networks, (b) RNA folding and RNA-RNA interactions can be well predicted, thus, a large number of novel devices can be build, (c) RNA production is energetically cheap, therefore the host cell is not affected by computing. The RiboNet toolbox will be created following a three-step process: (i) rational design and analysis of RNA-based devices on a computer, (ii) selecting best performers in vitro within highly parallel microfluidic reactors and, finally, (iii) integrating and testing them in living cells. The combination of all three layers of analysis, in silico, in vitro and in vivo, is a major point of this proposal. It will allow us to deal with complex regulatory networks and to examine the underlying mechanisms of information transmission and processing within cells.The toolbox developed by RiboNets will provide an outstanding prerequisite for novel designs in synthetic biology and life sciences. The usage of the RiboNet toolbox will result in the creation of RNA-based sensors and RNA-based devices with efficient regulation of engineered metabolic and signalling pathways that will have potential applications in white biotechnology and medicine. For example, RNA-based antibiotics would improve human condition in technological applications, as well as in health, in the future. With RiboNets, a new territory will be explored, shedding light on how RNA networks contribute to cell-to-cell information processing and communication. Champ scientifique natural sciencesbiological sciencessynthetic biologyengineering and technologyelectrical engineering, electronic engineering, information engineeringinformation engineeringtelecommunicationstelecommunications networksmobile networkmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsnatural sciencesbiological sciencesgeneticsRNAnatural sciencescomputer and information sciencesdata sciencedata processing Programme(s) FP7-ICT - Specific Programme "Cooperation": Information and communication technologies Thème(s) ICT-2013.9.3 - FET Young Explorers Appel à propositions FP7-ICT-2013-C Voir d’autres projets de cet appel Régime de financement CP - Collaborative project (generic) Coordinateur HEINRICH-HEINE-UNIVERSITAET DUESSELDORF Contribution de l’UE € 335 710,00 Adresse UNIVERSITAETSSTRASSE 1 40225 Dusseldorf Allemagne Voir sur la carte Région Nordrhein-Westfalen Düsseldorf Düsseldorf, Kreisfreie Stadt Type d’activité Higher or Secondary Education Establishments Contact administratif Katharina Kämmerer Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Participants (3) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire UNIVERSITAT WIEN Autriche Contribution de l’UE € 202 014,00 Adresse UNIVERSITATSRING 1 1010 Wien Voir sur la carte Région Ostösterreich Wien Wien Type d’activité Higher or Secondary Education Establishments Contact administratif Sven Findeiß (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée CHARITE - UNIVERSITAETSMEDIZIN BERLIN Participation terminée Allemagne Contribution de l’UE € 196 013,00 Adresse Chariteplatz 1 10117 Berlin Voir sur la carte Région Berlin Berlin Berlin Type d’activité Higher or Secondary Education Establishments Contact administratif Eveline Fraessdorf (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France Contribution de l’UE € 261 117,00 Adresse RUE MICHEL ANGE 3 75794 Paris Voir sur la carte Région Ile-de-France Ile-de-France Paris Type d’activité Research Organisations Contact administratif Bronislawa Domaszewska (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée