CORDIS
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Computational Horizons In Cancer (CHIC): Developing Meta- and Hyper-Multiscale Models and Repositories for In Silico Oncology

Ziel

Developing robust, reproducible, interoperable and collaborative hyper-models of diseases and normal physiology is a sine qua non necessity if rational, coherent and comprehensive exploitation of the invaluable information hidden within human multiscale biological data is envisaged. Responding to this imperative in the context of both the broad Virtual Physiological Human (VPH) initiative and the paradigmatic cancer domain, CHIC proposes the development of a suite of tools, services and secure infrastructure that will support accessibility and reusability of VPH mathematical and computational hypermodels. These will include a hypermodelling infrastructure consisting primarily of a hypermodelling editor and a hypermodelling execution environment, an infrastructure for semantic metadata management, a hypermodel repository, a hypermodel-driven clinical data repository, a distributed metadata repository and an in silico trial repository for the storage of executed simulation scenarios. Multiscale models and data will be semantically annotated using the ontological and annotating tools to be developed. An image processing and visualization toolkit, and cloud and virtualization services will also be developed. The CHIC tools, services, infrastructure and repositories will provide the community with a collaborative interface for exchanging knowledge and sharing work in an effective and standardized way. A number of open source features and tools will enhance usability and accessibility. In order to ensure clinical relevance and foster clinical acceptance of hypermodelling in the future, the whole endeavour will be driven by the clinical partners of the consortium. Cancer hypermodels to be collaboratively developed by the consortium cancer modellers will provide the framework and the testbed for the development of the CHIC technologies. Clinical adaptation and partial clinical validation of hypermodels and hypermodel oncosimulators will be undertaken.
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INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS

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10682 Athina

Griechenland

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Research Organisations

EU-Beitrag

€ 1 098 800

Kontakt Verwaltung

Georgios Stamatakos (Dr.)

Beteiligte (16)

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CUSTODIX NV

Belgien

EU-Beitrag

€ 240 375

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgien

EU-Beitrag

€ 615 000

UNIVERSITAET BERN

Schweiz

EU-Beitrag

€ 646 000

UNIVERSITAT DES SAARLANDES

Deutschland

EU-Beitrag

€ 1 272 996

GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER

Deutschland

EU-Beitrag

€ 469 928

EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH

Deutschland

EU-Beitrag

€ 640 498

TECHNOLOGICAL EDUCATIONAL INSTITUTE OF CRETE

Griechenland

EU-Beitrag

€ 87 040

IDRYMA TECHNOLOGIAS KAI EREVNAS

Griechenland

EU-Beitrag

€ 746 031

CINECA CONSORZIO INTERUNIVERSITARIO

Italien

EU-Beitrag

€ 320 560

UNIVERSITA DEGLI STUDI DI TORINO

Italien

EU-Beitrag

€ 457 998

PHILIPS ELECTRONICS NEDERLAND B.V.

Niederlande

EU-Beitrag

€ 566 120

THE UNIVERSITY OF SHEFFIELD

Vereinigtes Königreich

EU-Beitrag

€ 941 825

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

Vereinigtes Königreich

EU-Beitrag

€ 441 591

UNIVERSITY OF BEDFORDSHIRE

Vereinigtes Königreich

EU-Beitrag

€ 659 800

UNIVERSITY COLLEGE LONDON

Vereinigtes Königreich

EU-Beitrag

€ 804 156

University of Pennsylvania

Vereinigte Staaten

EU-Beitrag

€ 573 282

Projektinformationen

ID Finanzhilfevereinbarung: 600841

Status

Abgeschlossenes Projekt

  • Startdatum

    1 April 2013

  • Enddatum

    31 März 2017

Finanziert unter:

FP7-ICT

  • Gesamtbudget:

    € 13 939 060

  • EU-Beitrag

    € 10 582 000

Koordiniert durch:

INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS

Griechenland