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Clinical and system –omics for the identification of the MOlecular DEterminants of established Chronic Kidney Disease

Objective

iMODE-CKD integrates multi-disciplinary expertise in proteomics, metabolomics, transcriptomics, bioinformatics, pathology, and clinical science from leading academic and industrial investigators, establishing a unique training platform on biomarker research and Systems Biology. Special emphasis is placed on the application of a wide range of –omics and bioinformatics techniques to clinical research. This educational scope is placed in the context of a significant research objective: to improve quality of life of patients with chronic kidney disease (CKD) and diminish the severe health and economic burden imposed by this disease, by providing better diagnostic and prognostic means. Established CKD has been selected based on the accumulation of existing molecular data, and complementarity to active European programs focusing on early stage CKD in the context of diabetes and hypertension, in which participants of the consortium are actively involved. The main objectives of iMODE-CKD are:
- Training young scientists to become the next generation of true translational multidisciplinary researchers exploiting multiple -omics technologies to their full extent.
- Training young scientists in Systems Biology approaches to decipher molecular pathology and understanding clinical phenotypes.
- Identifying and validating molecules involved in progression of renal complications trough clinical –omics in established CKD.
- Understanding the molecular determinants of established CKD through integrative Systems Biology.
iMODE-CKD provides the opportunity to train young researchers not only in the different fields of -omics research, but also in -omics data evaluation, combining of datasets from different -omics traits, and exploiting both, data and literature, to enable the generation of in silico models of the molecular pathology of specific diseases. Such approaches will also enable development of new and specific drugs; and pave the road towards stratified/personalized medicine.

Call for proposal

FP7-PEOPLE-2013-ITN
See other projects for this call

Coordinator

IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON
Address
Soranou Efesiou 4
115 27 Athina
Greece
Activity type
Research Organisations
EU contribution
€ 746 065,62
Administrative Contact
Dimitris Raptis (Mr.)

Participants (10)

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 255 948,66
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
Muriel Bouas (Ms.)
MOSAIQUES DIAGNOSTICS GMBH
Germany
EU contribution
€ 418 369,60
Address
Rotenburger Strasse 20
30659 Hannover
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Petra Zürbig (Dr.)
Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE
North Macedonia
EU contribution
€ 167 511,30
Address
Blvd Goce Delcev 9
1000 Skopje
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Goce Spasovski (Prof.)
UNIVERSITY OF GLASGOW
United Kingdom
EU contribution
€ 285 056,64
Address
University Avenue
G12 8QQ Glasgow
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Derek Motherwell (Mr.)
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
Italy
EU contribution
€ 240 837,96
Address
Piazza Dell'ateneo Nuovo 1
20126 Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Fiorenza Coviello (Mrs.)
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany
EU contribution
€ 222 068,88
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Activity type
Research Organisations
Administrative Contact
Juergen Ertel (Dr.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN

Participation ended

Germany
EU contribution
€ 30 842,90
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eveline Fräßdorf (Ms.)
GENOMIC INVESTMENTS BV
Netherlands
EU contribution
€ 78 953,82
Address
Plesmanlaan 1D
2333 BZ Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pascal Berserik (Mr.)
UNIVERSITAETSKLINIKUM AACHEN
Germany
EU contribution
€ 191 225,98
Address
Pauwelsstrasse 30
52074 Aachen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Volker Legewie
GenomeScan B.V.
Netherlands
EU contribution
€ 157 907,64
Address
Plesmanlaan 1D
2333 BZ Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Cornelis Van Den Berg (Mr.)