CORDIS
EU research results

CORDIS

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"FLUOR21 : Synthesis, structure and function of fluorinated systems"

Project information

Grant agreement ID: 607787

Status

Closed project

  • Start date

    1 March 2014

  • End date

    28 February 2018

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 3 301 293,63

  • EU contribution

    € 3 301 293,63

Coordinated by:

UNIVERSITY OF DURHAM

United Kingdom

Objective

"Organofluorine chemistry has played a significant role in the majority of the spectacular scientific and technological developments of the
past century although this is not widely recognised even by the scientific community. Fluoroorganic molecules are key components in an
ever increasing number of high-value commercially important products particularly in the life science industries. The use of fluorinated
systems in drug discovery programmes has continued to grow and, at present, approximately 30% of new pharmaceutical and
agrochemical systems that enter the market bear fluorine atoms or fluorinated substituents, contributing enormously to the economic wellbeing
of the EU as a whole and the health of its citizens. All useful fluoroorganic systems are ‘man-made’ and the key step in developing
new products and applications involving fluorinated derivatives is the synthesis of carbon-fluorine bonds. We will develop new selective
fluorination processes by using both innovative chemoselective methodology and the emerging field of synthetic biology to provide new
technology platforms beyond the current state-of-the-art. The desire to introduce a fluorine atom into an organic system is often driven by
the fact that the C-F bond imparts unique and highly tuneable control of both geometric and stereoelectronic phenomena within a molecular
structure. The Network’s expertise in handling and analysing fluorinated molecules will allow us to engineer the properties of organic and
biological molecules through the strategic introduction of C-F bonds by molecular editing. A large number of world-leading research
scientists in academia in the various fields of organofluorine chemistry have retired in the recent past and, consequently, if training of ESRs
and support of youthful research groups is not continued, the EU will lose very competitive, highly valuable, high technology, research
expertise that contributes significantly to all chemical, life science and materials sectors."
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Coordinator

UNIVERSITY OF DURHAM

Address

Stockton Road The Palatine Centre
Dh1 3le Durham

United Kingdom

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 773 613,28

Administrative Contact

Wendy Harle (Ms.)

Participants (8)

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

Ireland

EU Contribution

€ 610 628,92

WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER

Germany

EU Contribution

€ 233 200

FREIE UNIVERSITAET BERLIN

Germany

EU Contribution

€ 233 200

USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.

Czechia

EU Contribution

€ 425 920

ASTRAZENECA AB

Sweden

EU Contribution

€ 232 272,06

THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

United Kingdom

EU Contribution

€ 290 556,64

UNIVERSITAT WIEN

Austria

EU Contribution

€ 245 750,56

ALMAC GROUP UK LIMITED

United Kingdom

EU Contribution

€ 256 152,17

Project information

Grant agreement ID: 607787

Status

Closed project

  • Start date

    1 March 2014

  • End date

    28 February 2018

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 3 301 293,63

  • EU contribution

    € 3 301 293,63

Coordinated by:

UNIVERSITY OF DURHAM

United Kingdom