CORDIS
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CORDIS

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Molecular Mechanisms of Fungal Pathogen Host Interactions

Project information

Grant agreement ID: 606786

Status

Closed project

  • Start date

    1 October 2013

  • End date

    30 September 2017

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 3 591 515

  • EU contribution

    € 3 591 515

Coordinated by:

MEDIZINISCHE UNIVERSITAET WIEN

Austria

Objective

ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the most common human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are: (i) to understand how immune cells and infected organs respond to invasion by Candida spp, (ii) to decipher host-defense mechanisms mediating pathogen elimination, and (iii) to identify genetic networks driving the dynamics of host-pathogen interplay. ImResFun will exploit cutting-edge technologies to unravel the basic mechanisms of fungal pathogenesis and host immunity, and to improve diagnosis and identify novel biomarkers of infection. Importantly, ImResFun will translate research into clinical practice and identify potential targets for antifungal drug discovery. ImResFun has seven WPs. In addition to coordination (WP7), research will cover molecular mechanisms of host-pathogen interactions using dual-system infection biology in vitro and in vivo (WP1), clinical patient setting and age-related infections (WP2), chemical biology and antifungal drug development (WP3), and bioinformatics and genome-wide data analysis (WP4). A compulsory and tailor-made practical course (WP5) and complementary skills (WP6) program will boost hypothesis-driven projects. Meaningful exposure to the private sector is ensured by extensive secondments of all ESRs/ERs. The resulting reciprocal technology transfer will be beneficial for both SMEs and ESR/ER hosts and sustain collaborations among partners. ImResFun will use personalized career development plans for each ESR/ER to train entrepreneurial scientists capable of translating frontier research into clinical practice, biotechnology and drug discovery. Taken together, ImResFun offers a best-practice example for interdisciplinary, intersectorial and supradisciplinary training in understanding the immunology of microbial infectious diseases, since most approaches are amenable to other microbial pathogens.

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN

Address

Spitalgasse 23
1090 Wien

Austria

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 843 298,10

Administrative Contact

Graham Warren (Prof.)

Participants (11)

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany

EU Contribution

€ 412 869,60

STOCKHOLMS UNIVERSITET

Sweden

EU Contribution

€ 259 925,16

UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS

Germany

EU Contribution

€ 222 068,88

KING'S COLLEGE LONDON

United Kingdom

EU Contribution

€ 285 056,64

FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI)

Czechia

EU Contribution

€ 205 208,52

EMC MICROCOLLECTIONS GMBH

Germany

EU Contribution

€ 222 068,88

UNIVERSIDAD COMPLUTENSE DE MADRID

Spain

EU Contribution

€ 226 681,62

SZEGEDI TUDOMANYEGYETEM

Hungary

EU Contribution

€ 197 255,52

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 226 681,62

LABDIA LABORDIAGNOSTIK GMBH

Austria

EU Contribution

€ 240 201,72

QIAGEN AARHUS AS

Denmark

EU Contribution

€ 250 198,74

Project information

Grant agreement ID: 606786

Status

Closed project

  • Start date

    1 October 2013

  • End date

    30 September 2017

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 3 591 515

  • EU contribution

    € 3 591 515

Coordinated by:

MEDIZINISCHE UNIVERSITAET WIEN

Austria