Obiettivo Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compounds are currently in clinical trials. Obviously we need new antibacterial molecules and maybe, novel strategies to develop antibiotics. The novel aspect here is to use state-in-the art techniques to quantify rate limiting steps of individual components involved antibiotic penetration and to validate them at the cellular level. Such a system biology approach identifies bottlenecks of existing antibiotics and might suggest novel antibiotic therapy. In Gram-negative bacteria, where influx and efflux systems located in the Outer Membrane represent a physical bottleneck for any antibiotic to reach a potential target. The aim is to investigate the molecular and cellular mechanisms at the basis of the influx and efflux processes and to teach scientists with different scientific background to go beyond theclassical faculty boarder. Bringing nanotechnology, physics, chemistry, computer modeling, pharmacology, microbiology together will facilitate the transfer of expertise acquired within the network in both academic and industry.To achieve these goals we propose a training program allowing young researcher to collaborate across traditional faculty boarder. Three partners from the private sector will actively participate, the first one is a SME developing unique nanodevices allowing high-throughput drug screening in the field of electrophysiology, the second one is engaged in developing novel antibiotics and the third one is working on drug screening and characterization. Moreover three global pharmaceutical companies will accept students for secondments. Campo scientifico natural sciencesbiological sciencesmicrobiologybacteriologyengineering and technologynanotechnologymedical and health sciencesclinical medicinepneumologytuberculosismedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsmedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancemultidrug resistance Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2013-ITN - Marie-Curie Action: "Initial Training Networks" Invito a presentare proposte FP7-PEOPLE-2013-ITN Vedi altri progetti per questo bando Meccanismo di finanziamento MC-ITN - Networks for Initial Training (ITN) Coordinatore CONSTRUCTOR UNIVERSITY BREMEN GGMBH Contributo UE € 625 640,18 Indirizzo CAMPUS RING 1 28725 Bremen Germania Mostra sulla mappa Regione Bremen Bremen Bremen, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Ronald Kieschnick (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (10) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITA DEGLI STUDI DI CAGLIARI Italia Contributo UE € 663 400,72 Indirizzo VIA UNIVERSITA 40 09124 Cagliari Mostra sulla mappa Regione Isole Sardegna Cagliari Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Luciano Colombo (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Costo totale Nessun dato THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS Regno Unito Contributo UE € 285 056,64 Indirizzo NORTH STREET 66 COLLEGE GATE KY16 9AJ St Andrews Mostra sulla mappa Regione Scotland Eastern Scotland Clackmannanshire and Fife Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Trish Starrs (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF NEWCASTLE UPON TYNE Regno Unito Contributo UE € 285 056,64 Indirizzo KINGS GATE NE1 7RU Newcastle Upon Tyne Mostra sulla mappa Regione North East (England) Northumberland and Tyne and Wear Tyneside Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Amanda Gregory (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN Germania Contributo UE € 222 068,88 Indirizzo THEODOR W ADORNO PLATZ 1 60323 Frankfurt Am Main Mostra sulla mappa Regione Hessen Darmstadt Frankfurt am Main, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Martin Pos (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITE D'AIX MARSEILLE Francia Contributo UE € 255 948,66 Indirizzo BOULEVARD CHARLES LIVON 58 LE PHARO 13284 Marseille Mostra sulla mappa Regione Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Celine Damon (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Costo totale Nessun dato UNIVERSITAT BASEL Svizzera Contributo UE € 261 515,76 Indirizzo PETERSPLATZ 1 4051 Basel Mostra sulla mappa Regione Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Dirk Bumann (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato BIOVERSYS AG Svizzera Contributo UE € 261 515,76 Indirizzo HOCHBERGERSTRASSE 60 C TECHNOLOGIEPARK BASEL 4057 Basel Mostra sulla mappa Regione Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Marc Gitzinger (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Germania Contributo UE € 222 068,88 Indirizzo HANSASTRASSE 27C 80686 Munchen Mostra sulla mappa Regione Bayern Oberbayern München, Kreisfreie Stadt Tipo di attività Research Organisations Contatto amministrativo Michael Prestele (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato NANION TECHNOLOGIES GMBH Germania Contributo UE € 222 068,88 Indirizzo GANGHOFERSTRASSE 70A 80339 Munchen Mostra sulla mappa Regione Bayern Oberbayern München, Kreisfreie Stadt Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Niels Fertig (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato European ScreeningPort GmbH Partecipazione conclusa Germania Contributo UE Nessun dato Indirizzo Schnackenburgallee 22525 Hamburg Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Philip Gribbon (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato