Objectif Imparting chirality to non-chiral metal surfaces by adsorption of chiral modifiers is a highly promising route to create effective heterogeneously catalyzed processes for production of enantiopure pharmaceuticals. A molecular-level understanding of enantioselective processes on chiral surfaces is an importance prerequisite for the rational design of new enantiospecific catalysts. With the research outlined in this proposal we are aiming at a fundamental level understanding of the structure of chirally modified surfaces, the bonding of the prochiral substrate on the chiral media and the details of the kinetics and dynamics of enantioselective surface reactions. A full mechanistic picture can be obtained if these aspects will be understood both on the extended single crystal surfaces, mimicking a local interaction of the modifier-substrate complexes with a metal, as well as on the small chirally modified nanoparticles that more accurately resemble the structural properties and high catalytic activity of practically relevant powdered supported catalyst. To achieve these atomistic insights, we propose to apply a combination of ultrahigh vacuum (UHV) based methods for studying reaction kinetics and dynamics (multi-molecular beam techniques) and in-situ surface spectroscopic and microscopic tools on well-defined model surfaces consisting of metal nanoparticles supported on thin single crystalline oxide films. Complementary, the catalytic behaviour of these chirally modified model surfaces will be investigated under ambient pressure conditions with enantiospecific detection of the reaction products that will enable detailed atomistic insights into structure-reactivity relationships. Champ scientifique medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural scienceschemical sciencescatalysisengineering and technologynanotechnologynano-materials Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-SG-PE4 - ERC Starting Grant - Physical and Analytical Chemical sciences Appel à propositions ERC-2013-StG Voir d’autres projets de cet appel Régime de financement ERC-SG - ERC Starting Grant Institution d’accueil CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Contribution de l’UE € 908 422,00 Adresse OLSHAUSENSTRASSE 40 24118 Kiel Allemagne Voir sur la carte Région Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt Type d’activité Higher or Secondary Education Establishments Chercheur principal Swetlana Schauermann (Dr.) Contact administratif Linda Piálek (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Allemagne Contribution de l’UE € 908 422,00 Adresse OLSHAUSENSTRASSE 40 24118 Kiel Voir sur la carte Région Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt Type d’activité Higher or Secondary Education Establishments Chercheur principal Swetlana Schauermann (Dr.) Contact administratif Linda Piálek (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Participation terminée Allemagne Contribution de l’UE € 681 314,00 Adresse HOFGARTENSTRASSE 8 80539 Munchen Voir sur la carte Région Bayern Oberbayern München, Kreisfreie Stadt Type d’activité Research Organisations Contact administratif Gert Von Helden (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
