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Collaborative European NeuroTrauma Effectiveness Research in TBI

Objective

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 patients, which will be used for better characterization of TBI and for Comparative Effectiveness Research (CER). The generalisability of our results will be reinforced by a contemporaneous registry level data collection in 15-25,000 patients. Our conceptual approach is to exploit the heterogeneity in biology, care, and outcome of TBI, to discover novel pathophysiology, refine disease characterization, and identify effective clinical interventions. Key elements are the use of emerging technologies (biomarkers, genomics and advanced MR imaging) in large numbers of patients, across the entire course of TBI (from injury to late outcome) and across all severities of injury (mild to severe). Improved characterization with these tools will aid Precision Medicine, a concept recently advocated by the US National Academy of Science, facilitating targeted management for individual patients. Our consortium includes leading experts and will bring outstanding biostatistical and neuroinformatics expertise to the project. Collaborations with external partners, other FP7 consortia, and international links within InTBIR, will greatly augment scientific resources and broaden the global scope of our research. We anticipate that the project could revolutionize our view of TBI, leading to more effective and efficient therapy, thus improving outcome and reducing costs. These outcomes reflect the goals of CER to assist consumers, clinicians, health care purchasers, and policy makers to make informed decisions, and will improve healthcare at both individual and population levels.

Call for proposal

FP7-HEALTH-2013-INNOVATION-1
See other projects for this call

Coordinator

UNIVERSITAIR ZIEKENHUIS ANTWERPEN
Address
Drie Eikenstraat 655
2650 Edegem
Belgium
Activity type
Research Organisations
EU contribution
€ 11 728 072
Administrative Contact
Tomas Menovsky (Prof.)

Participants (42)

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Participation ended

Finland
Address
Tekniikantie 4 A
02044 VTT Espoo
Activity type
Research Organisations
Administrative Contact
Jaana Heino (Ms.)
AZIENDA OSPEDALIERA SAN GERARDO DI MONZA

Participation ended

Italy
Address
Via Pergolesi 33
20052 Monza
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Enzo Vigutto (Mr.)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 2 997 529
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Renata Schaeffer (Ms.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 1 049 970
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Karin Buzzi-Donato (Ms.)
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 3 054 520
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Hester Lingsma (Dr.)
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Germany
EU contribution
€ 866 664
Address
Robert-koch-strasse 40
37075 Goettingen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christiane Hennecke (Mrs.)
TRNAVSKA UNIVERZITA V TRNAVE
Slovakia
EU contribution
€ 399 955
Address
Hornopotocna 23
918 43 Trnava
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Daniela Naništová (Mrs.)
PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS
Hungary
EU contribution
€ 1 652 438
Address
Vasvari Pal Utca 4
7622 Pecs
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Edina Kicsindi (Mrs.)
VARSINAIS-SUOMEN SAIRAANHOITOPIIRIN KUNTAYHTYMA
Finland
EU contribution
€ 48 596
Address
Kiinamyllynkatu 4-8
20520 Turku
Activity type
Research Organisations
Administrative Contact
Olli Tenovuo (Prof.)
ICOMETRIX NV
Belgium
EU contribution
€ 2 110 000
Address
Kolonel Begaultlaan 1B
3012 Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Dirk Smeets (Dr.)
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 533 706
Address
3 Avenue Victoria
75000 Paris
Activity type
Research Organisations
Administrative Contact
Alix Pillot (Ms.)
AZIENDA SOCIO-SANITARIA TERRITORIALE (ASST) DI MONZA

Participation ended

Italy
EU contribution
€ 61 741
Address
Via Giambattista Pergolesi 33
20900 Monza
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Enzo Vigutto (Mr.)
GENOME RESEARCH LIMITED

Participation ended

United Kingdom
Address
The Gibbs Building, Euston Road 215
NW1 2BE London
Activity type
Research Organisations
Administrative Contact
David Davison (Mr.)
MEDICAL RESEARCH COUNCIL

Participation ended

United Kingdom
Address
North Star Avenue Polaris House
SN2 1FL Swindon
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Sylvia Richardson (Dr.)
Private Universitaet Witten/Herdecke gGmbH
Germany
EU contribution
€ 376 324
Address
Alfred-herrhaussen Strasse 50
58455 Witten
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marc Maegele (Prof.)
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 163 858
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Wilco Peul (Prof.)
THE UNIVERSITY OF SHEFFIELD
United Kingdom
EU contribution
€ 401 775
Address
Firth Court Western Bank
S10 2TN Sheffield
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Andrew King (Mr.)
UNIVERSITE DE LIEGE
Belgium
EU contribution
€ 203 874
Address
Place Du 20 Aout 7
4000 Liege
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Isabelle Halleux (Prof.)
GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG

Participation ended

Germany
EU contribution
€ 173 130
Address
Oskar Von Miller Ring 29
80333 Muenchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Birgit Fuchs (Mrs.)
GREATER GLASGOW HEALTH BOARD
United Kingdom
EU contribution
€ 126 951
Address
Great Western Road 1055 J B Russell
G12 0XH Glasgow
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Brenda Colvin (Mrs.)
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
EU contribution
€ 85 000
Address
Im Neuenheimer Feld 672
69120 Heidelberg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Thorsten Brietz (Mr.)
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 211 676
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Shaun Power (Mr.)
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
Finland
EU contribution
€ 224 455
Address
Tekniikantie 21
02150 Espoo
Activity type
Research Organisations
Administrative Contact
Jaana Heino (Ms.)
THE UNIVERSITY OF STIRLING
United Kingdom
EU contribution
€ 224 684
Address
.
FK9 4LA Stirling
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eric Gibb (Mr.)
REGION HOVEDSTADEN
Denmark
EU contribution
€ 46 924
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Martin Fabricius (Dr.)
OSLO UNIVERSITETSSYKEHUS HF
Norway
EU contribution
€ 109 908
Address
Kirkeveien 166 Tarnbygget
0450 Oslo
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Cecilie Roe (Prof.)
OXFORD BROOKES UNIVERSITY
United Kingdom
EU contribution
€ 197 230
Address
Headington Campus Gipsy Lane
OX3 OBP Oxford
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Andrew Fleming (Mr.)
NHS BLOOD AND TRANSPLANT
United Kingdom
EU contribution
€ 22 100
Address
Oak House Reeds Crescent
WD24 4QN Watford
Activity type
Research Organisations
Administrative Contact
Simon Stanworth (Dr.)
FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO
Italy
EU contribution
€ 327 000
Address
Via Francesco Sforza 28
20122 Milano
Activity type
Other
Administrative Contact
Nino Stocchetti (Prof.)
HELSINGIN YLIOPISTO
Finland
EU contribution
€ 1 391 982
Address
Yliopistonkatu 3
00014 Helsingin Yliopisto
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mika Frederiksen (Mr.)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
United States
EU contribution
€ 93 225
Address
Franklin Street 1111, 12 Floor
94607 Oakland Ca
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mayra Sustaita (Mrs.)
UNIVERSITY OF FLORIDA
United States
EU contribution
€ 79 999
Address
Grinter Hall 223
32611 5500 Gainesville
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kevin Wang (Dr.)
University of Cincinnati
United States
EU contribution
€ 32 000
Address
Cincinnati,ohio
45221-0222 Cincinnati
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Carol Ross (Ms.)
MONASH UNIVERSITY
Australia
EU contribution
€ 279 499
Address
Wellington Road
3800 Victoria
Activity type
Higher or Secondary Education Establishments
Administrative Contact
D. James Cooper (Prof.)
AUCKLAND UNIVERSITY OF TECHNOLOGY
New Zealand
EU contribution
€ 25 000
Address
Queen Street Level 2 350
1020 Auckland
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Filomena Davies (Mrs.)
RENJI HOSPITAL SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
China
EU contribution
€ 50 000
Address
Dongfang Road 1630
200127 Shanghai
Activity type
Other
Administrative Contact
Ji-Yao Jiang (Prof.)
UNIVERSITAET GREIFSWALD
Germany
EU contribution
€ 19 000
Address
Domstrasse 11
17489 Greifswald
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Diana Lode (Mrs.)
INTERNATIONALE GESELLSCHAFT ZUR ERFORSCHUNG VON HIRNTRAUMATA
Austria
EU contribution
€ 10 346
Address
Molkergasse 3/4
1080 Wien
Activity type
Research Organisations
Administrative Contact
Walter Mauritz (Prof.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 37 000
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eveline Fräßdorf (Ms.)
ARTTIC
France
EU contribution
€ 355 168
Address
Rue Du Dessous Des Berges 58A
75013 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Martin Dietz (Dr.)
QUESGEN SYSTEMS, INC
United States
EU contribution
€ 127 500
Address
357 Beach Road
94010 Burlingame
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Jarrett (Mr.)
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
Italy
EU contribution
€ 100 104
Address
Piazza Dell'ateneo Nuovo 1
20126 Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Miriam Puttini (Dr.)