CORDIS
EU research results

CORDIS

English EN
Synthetic Biology for the production of functional peptides

Synthetic Biology for the production of functional peptides

Objective

"Peptides are among the most versatile natural products that nature provides to cater for a broad set of biotechnological applications ranging from antibiotics to personal hygiene. Their diversity comes from a broad variety of posttranslational modifications that is used to provide additional functionality beyond to what is possible with the classic proteinogenic set of 20 amino acids. In SYNPEPTIDE, we want to recruit such additional functionality for rational molecular design purposes in order to facilitate the design and the production of synthetic peptides.
To this end, we intend to standardize the integration of chemical diversity in peptide design and production by the following activities: [i] translational integration of chemically suitable non-canonical amino acids for posttranslational in vivo and in vitro modification; [ii] systematic recruitment of selected highly relevant posttranslational modifications from natural peptide synthesis routes into the design process. These activities will ultimately allow to drastically expand our arsenal of functionalities in the design of novel molecules and our capacity to reliably produce them."
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH

Address

Raemistrasse 101
8092 Zuerich

Switzerland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 892 804,80

Administrative Contact

Sven Panke (Prof.)

Participants (6)

Sort alphabetically

Sort by EU Contribution

Expand all

RIJKSUNIVERSITEIT GRONINGEN

Netherlands

EU Contribution

€ 939 363,20

TECHNISCHE UNIVERSITAT BERLIN

Germany

EU Contribution

€ 845 680

FGEN GMBH

Switzerland

EU Contribution

€ 719 163

UNIVERSITAET REGENSBURG

Germany

EU Contribution

€ 518 360

LANTHIOPEP BV

Netherlands

EU Contribution

€ 269 052

BIOFACTION KG

Austria

EU Contribution

€ 374 358

Project information

Grant agreement ID: 613981

Status

Closed project

  • Start date

    1 September 2013

  • End date

    31 August 2017

Funded under:

FP7-KBBE

  • Overall budget:

    € 7 170 757,60

  • EU contribution

    € 5 558 781

Coordinated by:

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH

Switzerland

This project is featured in...