Objetivo Powered by molecular tools, circadian research rapidly reveals a key role of biological rhythms in physiology and health, but clock function is poorly understood in its organismic and environmental context. Because clocks integrate multiple rhythmic processes, they need to be finely adjusted to environmental conditions. To address how genes and environment shape timekeeping, I combine frontline molecular tools and field-based approaches in the study of an avian model species in ecology and evolution, the Great Tit (Parus major). This research thrives on the complementarity of expertise and facilities of my host institution and the strengths that I bring. The project will lay the foundations for a long-term study system of biological time-keeping across levels of biological organization that will advance our understanding of the ways clocks aid fitness and health. Specifically, I will use cross-fostering designs and telemetry in the wild to test for early-environment effects on daily timing (’chronotype’), I will examine birds in captivity to quantify endogenous clock features, and use high-throughput molecular profiling technologies to advance the genotype-phenotype link in chronobiology. The research is based on my earlier findings of highly heritable, but nonetheless dynamic circadian clocks, which I can now greatly expand through the combined assets of the field station SCENE and the cutting-edge tools and analytical expertise for integrated analysis of multi-level ‘omic data at the University of Glasgow. The hosting Institute of Biodiversity, Animal Health and Comparative Medicine, is an internationally leading centre of multidisciplinary research with the mission of using ecological expertise to address urgent problems of today. With its unique focus and combination of approaches, the proposed research will bring novel perspectives to the institute and will boost my integration, while contributing significantly to understanding circadian clocks in real life. Ámbito científico natural sciencesbiological sciencesecologyecosystemsmedical and health sciencesbasic medicinephysiology Programa(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) FP7-PEOPLE-2013-CIG - Marie-Curie Action: "Career Integration Grants" Convocatoria de propuestas FP7-PEOPLE-2013-CIG Consulte otros proyectos de esta convocatoria Régimen de financiación MC-CIG - Support for training and career development of researcher (CIG) Coordinador UNIVERSITY OF GLASGOW Aportación de la UE € 100 000,00 Dirección UNIVERSITY AVENUE G12 8QQ Glasgow Reino Unido Ver en el mapa Región Scotland West Central Scotland Glasgow City Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Joe Galloway (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos
