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Deciphering inter- and intracellular signalling in schizophrenia

Objective

IN-SENS is an interdisciplinary, cutting-edge European industry-academia collaborative effort for a novel training of scientists in molecular psychiatry with the prospect of discovering the biology of schizophrenia and actively promote drug discovery. Mental illnesses are a major burden to patients, relatives, and public health worldwide. IN-SENS therefore aims to profoundly change the academic-industry research landscape in European psychiatry by an unprecedented, innovative strategy.

The extended intra- and intercellular signalling pathway of disrupted-in-schizophrenia 1 (DISC1), the best characterized gene known to cause schizophrenia and other chronic mental illnesses (CMI), will be used as a molecular Rosetta stone for this purpose. Expected results of IN-SENS include profound training, including clinical psychiatry, industrial, and translational medicine exposure, of a new generation of European ESRs capable of understanding the molecular underpinnings of CMI in academia, industry and other non-academic sectors. ESRs will explore how molecules related to the extended DISC1 pathway translate to the different biochemical, genetic, and neurodevelopmental hypotheses and data proposed so far as being important players in the molecular pathology of CMI. Further, they will play an active role in the generation of new analytical tools and therapeutic agents for the diagnosis and treatment of CMI in close collaboration with the industrial sector.
IN-SENS will have immediate and longterm benefits for the European academic-industry research landscape in psychiatry by fostering scientific creativity and entrepreneurial skills of ESRs, generating novel research networks in Europe, enhancing mutual recognition and introducing novel models and of public-private cooperations. At the end of IN-SENS, exceptionally trained ESRs will be ready to extend these studies in academia and/or the private sector, and be able to move confidently to a fruitful professional career.

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /medical and health sciences/basic medicine/pathology
  • /medical and health sciences/clinical medicine/psychiatry
  • /medical and health sciences/clinical medicine/psychiatry/schizophrenia

Call for proposal

FP7-PEOPLE-2013-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Address
Universitaetsstrasse 1
40225 Dusseldorf
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 656 445,03
Administrative Contact
Doris Neubert

Participants (12)

UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Spain
EU contribution
€ 226 681,62
Address
Colexio De San Xerome Praza Do Obradoiro S/n
15782 Santiago De Compostela
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Martin Cacheiro Martinez (Mr.)
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 236 861,47
Address
Minderbroedersberg 4-6
6200 MD Maastricht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Willem Wolters (Mr.)
KUNGLIGA TEKNISKA HOEGSKOLAN
Sweden
EU contribution
€ 259 925,16
Address
Brinellvagen 8
100 44 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marianne Fridborn (Mrs.)
STICHTING VU
Netherlands
EU contribution
€ 478 122,92
Address
De Boelelaan 1105
1081 HV Amsterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Yvonne Kops (Dr.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 285 056,64
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kirsty Millar (Dr.)
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria
EU contribution
€ 240 201,72
Address
Am Campus 1
3400 Klosterneuburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Barbara Abraham (Ms.)
SYNAPTOLOGICS BV
Netherlands
EU contribution
€ 456 861,47
Address
Achillesstraat 28 2
1008 BA Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Evelyn Van Royen (Mrs.)
HELSINGIN YLIOPISTO
Finland
EU contribution
€ 261 197,64
Address
Yliopistonkatu 3
00014 Helsingin Yliopisto
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Katariina Vainio-Mattila (Ms.)
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 222 068,88
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Peter Falkai (Prof.)
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 285 056,64
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Oliver Howes (Dr.)
ASTRAZENECA AB
Sweden
EU contribution
€ 154 312,41
Address
Vastra Maelarhamnen
151 85 Sodertaelje
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lars Farde (Prof.)
F. HOFFMANN-LA ROCHE AG
Switzerland
EU contribution
€ 155 346,40
Address
Grenzacherstrasse 124
4070 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jason Hannon (Dr.)