Project description Heterogeneous Integration and take-up of of Key Enabling Technologies for Components and Systems Show the project objective Hide the project objective Through further development, integration and validation of micro-nano-bio and biophotonics systems from previous projects CanDo will develop an instrument that will permit the identification and concentration determination of rare cells in peripheral blood for two key societal challenges, early and low cost anti-cancer drug efficacy determination and cancer diagnosis/monitoring.A cellular link between the primary malignant tumor and the peripheral metastases, responsible for 90% of cancer-related deaths, has been established in the form of circulating tumor cells (CTCs) in peripheral blood. Furthermore the relatively short survival time of CTCs in peripheral blood means that their detection is indicative of tumor progression thereby providing in addition to a prognostic value an evaluation of therapeutic efficacy and early recognition of tumor progression in theranostics. In cancer patients however blood concentrations are very low (=1 CTC/1E9 cells) and current detection strategies are too insensitive, limiting use to prognosis of only those with advanced metastatic cancer. Similarly problems occur in therapeutics with anti-cancer drug development leading to lengthy and costly trials often preventing access to market. There is therefore a clear need for a novel analytical platform capable of highly reproducible and reliable identification of CTC concentrations of interest in an easily accessible format.With all relevant industrial stakeholders and users onboard CanDo is uniquely capable of delivering such a platform. Its novel cell separation/SERS analysis technologies plus nucleic acid based molecular characterization will provide an accurate CTC count with high throughput and high yield meeting both key societal challenges. Being beyond the state of art it will lead to substantial share gains not just in the high end markets of drug discovery and cancer diagnostics but due to modular technologies in others e.g. transport, security and safety and environment. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsmedical and health sciencesclinical medicineoncology Programme(s) FP7-ICT - Specific Programme "Cooperation": Information and communication technologies Topic(s) ICT-2013.3.3 - Heterogeneous Integration and take-up of Key Enabling Technologies for Components and Systems Call for proposal FP7-ICT-2013-10 See other projects for this call Funding Scheme CP - Collaborative project (generic) Coordinator UNIVERSITAT DE VALENCIA Address Avenida blasco ibanez 13 46010 Valencia Spain See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Angeles Sanchis (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 501 501,00 Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM Belgium EU contribution € 461 833,00 Address Kapeldreef 75 3001 Heverlee See on map Activity type Research Organisations projects.administrative_contact Christine Van Houtven (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Bayer Pharma AG Germany EU contribution € 253 685,00 Address Muellerstrasse 178 13353 Berlin See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Thomas Krahn (Dr.) Links Contact the organisation Opens in new window Website Opens in new window LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. Germany EU contribution € 311 013,00 Address Albert einstein strasse 9 07745 Jena See on map Activity type Research Organisations projects.administrative_contact Gabriele Hamm (Ms.) Links Contact the organisation Opens in new window Website Opens in new window GILUPI GMBH Germany EU contribution € 290 946,00 Address Am muehlenberg 11 14476 Postdam See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Klaus Luecke (Dr.) Links Contact the organisation Opens in new window Website Opens in new window MICROFLUIDIC CHIPSHOP GMBH Germany EU contribution € 496 857,00 Address Stockholmer strasse 20 07747 Jena See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Claudia Gärtner (Dr.) Links Contact the organisation Opens in new window Website Opens in new window IKERLAN S. COOP Spain EU contribution € 391 264,00 Address P jose maria arizmendiarrieta 2 20500 Mondragon See on map Activity type Research Organisations projects.administrative_contact Chris Merveille (Dr.) Links Contact the organisation Opens in new window Website Opens in new window STOCKHOLMS UNIVERSITET Sweden EU contribution € 400 312,00 Address Universitetsvagen 10 10691 Stockholm See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Ann Nielsen (Ms.) Links Contact the organisation Opens in new window Website Opens in new window KUNGLIGA TEKNISKA HOEGSKOLAN Sweden EU contribution € 549 409,00 Address Brinellvagen 8 100 44 Stockholm See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Marianne Fridborn (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window REGION STOCKHOLM Sweden EU contribution € 343 180,00 Address Hantverkargatan 45 104 22 Stockholm See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) projects.administrative_contact Erica Oeqvist Links Contact the organisation Opens in new window Website Opens in new window
