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BACterial Hosts for production of Bioactive phenolics from bERRY fruits

Project information

Grant agreement ID: 613793

Status

Closed project

  • Start date

    1 November 2013

  • End date

    31 October 2016

Funded under:

FP7-KBBE

  • Overall budget:

    € 9 520 459,03

  • EU contribution

    € 7 297 873,80

Coordinated by:

DANMARKS TEKNISKE UNIVERSITET

Denmark

Objective

Plants synthesize a staggering variety of secondary metabolites, and this chemodiversity is a poorly used pool of natural molecules with bioactive properties of importance for applications in the pharma and food industries. BacHBerry focusses on phenolic compounds, a large and diverse class of plant metabolites, which are currently in the spotlight due to their claimed beneficial effects in prevention and treatment of chronic diseases, but that also have applications as cosmetics, flavours and food colorants etc. Berries are soft and colourful fruits, with great diversity, high content and unique profiles in phenolic compounds, making them a major source of these high-value metabolites. The BacHBerry project aims to develop a portfolio of sustainable methodologies to mine the potential of the untapped biodiversity of the bioactive phenolic compounds in an extensive collection of berry species. Full exploitation of this unrivalled natural resource requires an integrated and comprehensive effort from bioprospecting in berries using SMART high-throughput screens for the valorisation of phenolic bioactivities aligned with their identification using cutting edge analytics and subsequent elucidation of their biosynthetic pathways. This knowledge will facilitate metabolic engineering of suitable bacterial hosts for high-value phenolics production in scalable fermentation bioprocesses, ultimately serving as commercial production platforms. The consortium comprises a full chain of research and innovation, with 12 research groups, 5 SMEs and a large enterprise, representing 10 countries including partners from ICPC countries Russia, Chile and China, with the capacity to exploit novel bioactivities from berry fruits diversity. BacHBerry develops a pipeline of sustainable and cost-effective processes to facilitate production of added-value berry phenolics with immediate potential for commercialization and consequent socio-economic benefits for the European community and beyond.

Coordinator

DANMARKS TEKNISKE UNIVERSITET

Address

Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby

Denmark

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 220 009,22

Administrative Contact

Birte Rasmussen

Participants (18)

INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA

Portugal

EU Contribution

€ 511 446

THE JAMES HUTTON INSTITUTE

United Kingdom

EU Contribution

€ 472 110

JOHN INNES CENTRE

United Kingdom

EU Contribution

€ 549 292

KOBENHAVNS UNIVERSITET

Denmark

EU Contribution

€ 441 028,03

RIJKSUNIVERSITEIT GRONINGEN

Netherlands

EU Contribution

€ 329 303

FORSCHUNGSZENTRUM JULICH GMBH

Germany

EU Contribution

€ 578 827,25

TECHNISCHE UNIVERSITEIT DELFT

Netherlands

EU Contribution

€ 549 466

INSTITUTO DE ENGENHARIA MECANICA

Portugal

EU Contribution

€ 350 140

INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE

France

EU Contribution

€ 404 737,80

BIOFACTION KG

Austria

EU Contribution

€ 549 250

EVOLVA BIOTECH A/S

Denmark

EU Contribution

€ 374 444

CHR. HANSEN A/S

Denmark

EU Contribution

€ 131 401,50

BIOTEMPO - CONSULTORIA EM BIOTECNOLOGIA LDA

Portugal

EU Contribution

€ 462 360

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

EU Contribution

€ 38 775

INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES

China

EU Contribution

€ 104 429

RUSSIAN STATE SCIENTIFIC INSTITUTION N.I. VAVILOV ALL-RUSSIAN RESEARCH INSTITUTE OF RUSSIAN ACADEMY OF AGRICULTURAL SCIENCES

Russia

EU Contribution

€ 62 100

NORFOLK PLANT SCIENCES LIMITED

United Kingdom

EU Contribution

€ 63 793

CHR. HANSEN NATURAL COLORS AS

Denmark

EU Contribution

€ 104 962

Project information

Grant agreement ID: 613793

Status

Closed project

  • Start date

    1 November 2013

  • End date

    31 October 2016

Funded under:

FP7-KBBE

  • Overall budget:

    € 9 520 459,03

  • EU contribution

    € 7 297 873,80

Coordinated by:

DANMARKS TEKNISKE UNIVERSITET

Denmark