Skip to main content

Reinforced Bioresorbable Biomaterials for Therapeutic Drug Eluting Stents

Objective

Active therapeutic biodegradable and biocompatible materials are highly in demand. These are required for the production of medicinal products in a variety of areas including implant technology, tissue engineering, drug delivery and wound healing. Within implant technology such biomaterials can be used for dental, bone and cardiovascular implants. Tailored mechanical properties, biocompatibility and degradation rate is the key to the development for a specific implant.

Stents are tubular type implants that are deployed most commonly to recover the shape of narrowed arterial segments. Although, the clinical use of stents is widespread, they cause adverse responses including inflammation, in-stent restenosis and thrombosis. Endothelialisation of the stent greatly reduces these adverse reactions. In contrast to permanent stents there is great attraction in the notion of a biodegradable stent that recovers and maintains arterial shape and then gradually disappears and avoids further complications.

In this multi-institution & disciplinary SME focussed project we will aim to provide the technological framework that leads to the production of reinforced polymeric biomaterials tailored towards stent manufacturing without adverse effects. Both natural and synthetic polymers will be produced and used. These will be reinforced and functionalised using a variety of techniques. Controlled delivery of suitable positive additives including antimitotic factors will be aimed for and their release monitored. These highly functionalised active biomaterials will be characterised thoroughly for material properties, biocompatibility, rate of biodegradation and used for the production of ideal stents. These will be characterized thoroughly leading to preclinical validation. All required production and manufacturing guidelines will be followed.

Field of science

  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug
  • /medical and health sciences/medical biotechnology/tissue engineering
  • /natural sciences/chemical sciences/polymer science
  • /engineering and technology/industrial biotechnology/biomaterials
  • /medical and health sciences/medical biotechnology/medical bioproducts/implants

Call for proposal

FP7-NMP-2013-SME-7
See other projects for this call

Funding Scheme

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinator

LUCIDEON LIMITED
Address
Queens Road Penkhull
ST4 7LQ Stoke On Trent
United Kingdom
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 624 500
Administrative Contact
Xiang Zhang (Dr.)

Participants (13)

THE UNIVERSITY OF WESTMINSTER LBG
United Kingdom
EU contribution
€ 578 972
Address
Regent Street 309
W1B 2UW London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ipsita Roy (Mrs.)
ASHLAND SPECIALTIES IRELAND LIMITED
Ireland
EU contribution
€ 317 990
Address
Synergy Centre, Laboratory A, Technological University Dublin (Tu Dublin), Tallaght
D24 A386 Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Colm Odowd (Dr.)
SPINTEC ENGINEERING GMBH

Participation ended

Germany
EU contribution
€ 100 072,80
Address
Kurbrunnenstrasse 22
52066 Aachen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Wöltje (Dr.)
ARTERIUS LIMITED
United Kingdom
EU contribution
€ 366 326,20
Address
Bradford Bio Incubator Bradford
BD7 IDP Bradford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Kadem Al-Lamee (Mr.)
POLITECNICO DI TORINO
Italy
EU contribution
€ 241 946
Address
Corso Duca Degli Abruzzi 24
10129 Torino
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marica Pertile (Dr.)
UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 358 863
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Yan Qiao (Mrs.)
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany
EU contribution
€ 218 400
Address
Schlossplatz 4
91054 Erlangen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ulrike Hoffmann (Mrs.)
FUNDACION TEKNIKER
Spain
EU contribution
€ 267 293
Address
Calle Inaki Goenaga 5
20600 Eibar Guipuzcoa
Activity type
Research Organisations
Administrative Contact
Patricia Martín Bao (Ms.)
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 470 035
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
Administrative Contact
Walter Krause (Mr.)
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 208 315
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Renata Schaeffer (Ms.)
RUHR-UNIVERSITAET BOCHUM
Germany
EU contribution
€ 325 586
Address
Universitaetsstrasse 150
44801 Bochum
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jochen Salber (Mr.)
LIFE AND DEVICE SRL
Italy
EU contribution
€ 296 025
Address
Via Gioacchino Quarello 11 A
10135 Torino
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mimmo Falzone (Mr.)
EURESCOM-EUROPEAN INSTITUTE FOR RESEARCH AND STRATEGIC STUDIES IN TELECOMMUNICATIONS GMBH
Germany
EU contribution
€ 204 807
Address
Wieblinger Weg 19/4
69123 Heidelberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Maria Barros Weiss (Dr.)