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Novel combination of biopolymers and manufacturing technologies for production of a peripheral nerve implant containing an internal aligned channels array

Objective

"Peripheral nerves are basic communication structures guiding motor and sensitive information from CNS to effector or receptor units. Severe nerve injuries include axon bundles section and Schawnn cells destruction, which results in loss of motion control and sensorial perception. After the lesion, cells present in damaged nerves activate spontaneously self-regeneration programs that might facilitate further treatment. Nerve autograft is the “gold standard” surgical intervention that demands autologous tissue extraction and corresponding function loss. The goal of the project is the validation of biomaterials structural plasticity and those compatible manufacturing technologies that will enable the generation of a tubular structure containing an intraluminal microstructure based on an array of aligned channels or fibers. The regenerative properties of this prototype will be also validated in vivo in a sciatic nerve section animal model. This project proposal will take advantage of partners’ experience in the design of medical devices composed of natural and synthetic biomaterials and in scaled-up production mechanization technologies for the generation of the most effective peripheral nerve implant."

Field of science

  • /engineering and technology/industrial biotechnology/biomaterials

Call for proposal

FP7-NMP-2013-SME-7
See other projects for this call

Funding Scheme

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinator

FUNDACION TEKNIKER
Address
Calle Inaki Goenaga 5
20600 Eibar Guipuzcoa
Spain
Activity type
Research Organisations
EU contribution
€ 663 889
Administrative Contact
Saioa Mondragon (Ms.)

Participants (7)

HISTOCELL SL
Spain
EU contribution
€ 439 839
Address
Parque Tecnologico De Bizkaia Edificio 801 Piso 2
48160 Derio Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Eva Gonzalez (Dr.)
CONTIPRO AS
Czechia
EU contribution
€ 303 960
Address
Dolni Dobrouc 401
561 02 Dolni Dobrouc
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Eva Cerna (Dr.)
THE UNIVERSITY OF SHEFFIELD
United Kingdom
EU contribution
€ 553 988
Address
Firth Court Western Bank
S10 2TN Sheffield
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Joanne Watson (Ms.)
ASHLAND SPECIALTIES IRELAND LIMITED
Ireland
EU contribution
€ 395 293
Address
Synergy Centre, Laboratory A, Technological University Dublin (Tu Dublin), Tallaght
D24 A386 Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Colm Odowd (Dr.)
THE UNIVERSITY OF WESTMINSTER LBG
United Kingdom
EU contribution
€ 504 053
Address
Regent Street 309
W1B 2UW London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ipsita Roy (Dr.)
SERVICIO DE SALUD DE CASTILLA LA MANCHA
Spain
EU contribution
€ 445 738
Address
Avenida Rio Guadiana 4
45007 Toledo
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Juan Fernandez (Dr.)
Qserve Consultancy BV
Netherlands
EU contribution
€ 102 780
Address
Gordel Van Smaragd 23
1448 AE Purmerend
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Esmeralda Van De Water (Mrs.)